Results 201 to 210 of about 45,362 (276)

Tackling the Reactivity of Propadiene: Palladium Metallaphotoredox Dual Catalyzed Multi‐Component Allylation and Dienylation of Styrenes

Angewandte Chemie, Volume 138, Issue 4, 22 January 2026.
We presented herein that propadiene can chemodivergently form either an allylic moiety or a dienylic moiety under Pd catalysis. Embedding this reactivity pattern into photocatalysis with DHP as the initial radical source and styrene derivatives as the initial acceptor leads to multi‐component allylation and dienylation.
Yi‐Fei Yang, Felix Bauer, Bernhard Breit   +2 more
wiley   +2 more sources

RuO4-mediated oxidation of N-benzylated tertiary amines. 3. Behavior of 1,4-dibenzylpiperazine and its oxygenated derivatives

Open Chemistry, 2006
Petride Horia, Drăghici Constantin, Florea Cristina, Petride Aurica   +3 more
doaj   +1 more source

Controlling the Regioselectivity of Topochemical Reduction Reactions Through Sequential Anion Insertion and Extraction. [PDF]

Angew Chem Int Ed Engl
Wernert R, Batnaran B, Hayward MA.
europepmc   +1 more source

π‐Expanded Nitrogen‐Cation (N+)‐Doped Polycyclic Aromatic Hydrocarbons: A Review of Intramolecular Cyclization Routes to Benzo[c]Quinolizinium, Triazinium, Pyridoquinazolinium, and Pyridoquinoxalinium Frameworks

European Journal of Organic Chemistry, Volume 29, Issue 4, January 26, 2026.
This review surveys recent progress in the synthesis of extended aromatic quinolizinium derivatives via intramolecular SNAr and oxidative 6π‐electrocyclization. Conventional thermal approaches are discussed alongside emerging, sustainable activation methods such as electrosynthesis and photochemical processes.
Marine Labro, Cyrille Monnereau, Laure Guy   +2 more
wiley   +1 more source

Bench‐Stable Boryl Thianthrenium Dication Enables Aziridinyl Boronate Synthesis via Metal‐Free Late‐Stage Aziridination with Diverse Nitrogen Nucleophiles

Angewandte Chemie, Volume 138, Issue 4, 22 January 2026.
A bench‐stable boryl thianthrenium dication is synthesized via thianthrenation of vinyl MIDA boronate. This novel dication enables metal‐free, chemo‐, and diastereoselective late‐stage aziridination with diverse nitrogen nucleophiles. The strategic significance is further showcased by one‐pot electrochemical and asymmetric protocols and versatile ...
Veerabhadra R. Vulupala, Disni Gunasekera, Nagarjun R. Mallampudi, Ramy Yousef, Yusif I. Gyasi, Gopal R. Ramidi, Ifeoluwa Adedotun, Shiqing Xu   +7 more
wiley   +2 more sources

Intra‐ and Intermolecular Glycosylation of d‐Idopyranosyl and 6‐Deoxy‐d‐ido‐heptopyranosyl Donors: Toward the Repeating Unit of Campylobacter jejuni HS:4c Capsular Polysaccharide

European Journal of Organic Chemistry, Volume 29, Issue 4, January 26, 2026.
A comprehensive glycosylation study of diversely protected and activated d‐idopyranosyl and 6‐deoxy‐d‐ido‐heptopyranosyl donors using intra‐ and intermolecular coupling strategies is reported. Intramolecular aglycon delivery afforded 1,2‐cis‐β‐idopyranosides, while intermolecular glycosylation yielded chromatographically separable α‐ and β‐linked ...
Maude Cloutier, Nitish Verma, Ilona Douchez, Charles Gauthier   +3 more
wiley   +1 more source

Divergent Total Synthesis of Denudatine Alkaloids Cochlearenine, Macrocentrine, Dictizine, 15‐Veratroyl‐17‐Acetyl‐19‐Oxodictizine, and the Proposed Structure of Acochlearine

Angewandte Chemie, Volume 138, Issue 4, 22 January 2026.
An intramolecular Mannich reaction (A/B/E/F rings) and intermolecular Diels–Alder reactions (C/D rings) afforded a cage‐like hexacyclic core skeleton of denudatine alkaloids. Derivatization of the hexacyclic intermediate enabled the first asymmetric total syntheses of four denudatine alkaloids: (–)‐cochlearenine, (–)‐macrocentrine, (–)‐dictizine, and (–
Shun Kawano, Naoya Miyamoto, Kosuke Fujioka, Hiroki Toya, Juri Sakata, Hidetoshi Tokuyama   +5 more
wiley   +2 more sources

Nickel-Catalyzed cine-Substitution Toward Carbonyl Dance. [PDF]

Chem Asian J
Moriya E, Muto K, Yamaguchi J.
europepmc   +1 more source

Caylobolide B: Structure Revision, Total Synthesis, Biological Characterization, and Discovery of New Analogues

Angewandte Chemie, Volume 138, Issue 4, 22 January 2026.
Marine polyhydroxylated macrolides’ drug discovery potential is limited by structural complexity and scarce material supply, hindering structure assignment, synthesis, and biological studies. Here, we present an integrated workflow that combines chemogenomic profiling, ultra‐high‐resolution NMR‐guided structural revision and stereochemical assignment ...
Malcolm R. P. George, Lobna A. Elsadek, Max Deering, Larissa Costa de Almeida, Jasper L. Tyler, Adam Noble, Valerie J. Paul, Hendrik Luesch, Craig P. Butts, Varinder K. Aggarwal   +9 more
wiley   +2 more sources