Results 191 to 200 of about 37,566 (244)

DNA‐Barcoded Polysaccharide Specific Monoclonal Antibodies Facilitate Sensitive and Multiplexed Detection of Cell Wall Polymers

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT Plant cell walls are polysaccharide‐rich extracellular matrices composed of multiple complex carbohydrate polymer networks, including cellulose, hemicelluloses, pectins, and glycosylated proteins. Polysaccharide deposition critically impacts cell wall structure, and structural microheterogeneity within cell wall glycans also influences polymer
C. Frankie Griffith   +2 more
wiley   +1 more source

Chemoselective Generation of the 1,3-Benzdiyne Synthon. [PDF]

open access: yesJ Org Chem
Barnå F   +5 more
europepmc   +1 more source

Hydroxyaldehyde and formyl photoproducts of protoporphyrin IX formed under photodynamic diagnosis and therapy irradiation conditions

open access: yesPhotochemistry and Photobiology, EarlyView.
Photoproducts of the photosensitizer protoporphyrin IX (PpIX) may have diagnostic and therapeutic relevance in photodynamic diagnosis (PDD) and photodynamic therapy (PDT). These photoproducts possess fluorescence and photosensitizing properties and could serve as a complementary dosimetry index alongside photosensitizer photobleaching. The formation of
Sochi J. Ogbonna   +2 more
wiley   +1 more source

Surface Ligand Engineering in Quantum Dot Photocatalysis: Mechanisms, Design Principles, and Applications

open access: yesAdvanced Chemical Engineering, Volume 1, Issue 2, December 2026.
Surface ligands govern quantum dot photocatalysis through thermodynamic band‐edge tuning, kinetic charge‐transfer regulation, and microenvironmental control. Rational ligand engineering, using short‐chain, inorganic, conjugated, or dual‐ligand systems, enables efficient solar fuel production, selective organic transformations, environmental remediation,
Yali Weng   +5 more
wiley   +1 more source

1‐Azabicyclo[1.1.0]butanes (ABBs) on the Map: Mechanistic Pathways for Catalytic Ring Opening and Functionalizations

open access: yesAngewandte Chemie, Volume 138, Issue 46, 9 November 2026.
Catalytic strain‐release ring opening and functionalizations of 1‐azabicyclo[1.1.0]butanes (ABBs) represent a promising strategy for accessing diverse azetidine products. These transformations proceed via polar pathways, radical pathways, and hybrid mechanisms that combine both.
James Shao‐Jiun Yang   +1 more
wiley   +2 more sources

Copper‐Mediated Radiofluorination of the Excitatory Amino Acid Transporter 2 (EAAT2)–Targeted PET Tracer [18F]RP‐115: Alternate Synthetic Method

open access: yesJournal of Labelled Compounds and Radiopharmaceuticals, Volume 69, Issue 13-14, November-December 2026.
An efficient two‐step radiosynthesis of [18F]RP‐115 was developed using copper‐mediated radiofluorination (CMRF) followed by deprotection. In a total 70‐min synthesis time, this approach provided [18F]RP‐115 in high radiochemical yield (52.8% ± 2.1%, decay corrected from stating [18F]fluoride ion) with high molar activity (355 ± 61 GBq/μmol) and ...
Sang Hee Lee   +9 more
wiley   +1 more source

Breakthrough Design of Highly Potent Antivirals Against Wild‐Type HIV‐1 and Lenacapavir‐Resistant M66I Variant

open access: yesAngewandte Chemie, Volume 138, Issue 46, 9 November 2026.
Lenacapavir, the first‐in‐class drug targeting HIV‐1 capsid, is a breakthrough drug in HIV‐1 treatment and prophylaxis. However, a single M66I mutation confers complete viral resistance to lenacapavir. We report herein the design and synthesis of innovative R2 analogs demonstrating low nM potency against HIV‐1 M66I and excellent pharmacokinetics in ...
Nicolas Jamey   +13 more
wiley   +2 more sources

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