Results 201 to 210 of about 32,974 (279)

Pd-catalyzed regioselective synthesis of 3-aminoindoles <i>via</i> Larock-type annulation of <i>N</i>-protected 2-iodoanilines with ynamides. [PDF]

Chem Sci
Chen R, Zhang J, Chang J, Wang XN.
europepmc   +1 more source

N‐Sulfonyl Azalevoglucosan: A Versatile Platform for the Synthesis of Polysubstituted Piperidines

Chemistry – A European Journal, EarlyView.
Gain by strain: The synthesis of a levoglucosan analog, in which the pyranose oxygen has been replaced by a nitrogen, allows navigation on the piperidine ring to iteratively install functional groups at C1, C2, C3, C4, and C6 positions using simple experimental protocols with minimal protecting group manipulation.
Dylan Yorga, Jérôme Marrot, Ana Poveda, Nicolas Auberger, Jesús Jiménez‐Barbero, Jérôme Désiré, Yves Blériot   +6 more
wiley   +1 more source

A Stable Isopterin Mimic of a Potent Bacterial Stimulant of T Cells

Chemistry – A European Journal, EarlyView.
A microbial metabolite covalently binds immunological protein MR1 to potently activate specific lymphocytes called MAIT cells, but it is too unstable for biological applications. Here, using synthesis, assays, protein crystallography, and computer modelling, we report a water‐stable analogue that activates reporter cells expressing the MAIT T cell ...
Jeffrey Y. W. Mak, Huy N. Hoang, Wael Awad, Xin Yi Lim, Damica D. Laurie, Ryan J. D. Rivero, James McCluskey, Alexandra J. Corbett, Jamie Rossjohn, David P. Fairlie   +9 more
wiley   +1 more source

A programmable bifunctional flavoenzyme for direct amine-to-ester conversion. [PDF]

Sci Adv
Wu Y, Song W, Wei W, Liu L, Wu J.
europepmc   +1 more source

Multi‐Scale Investigation of Supramolecular Organogels Assembled From Pt(II)‐Salphen Complexes

Chemistry – A European Journal, EarlyView.
A family of Pt(II)‐salphen complexes with long alkyl chains is investigated as low‐molecular‐weight organogelators. Multi‐scale characterization of their supramolecular gels reveals how the chain length, Pt‐Pt interactions, and π–π stacking direct self‐assembly and tune gel mechanics.
Pablo Msellem, Davide Condotta, Lise‐Marie Chamoreau, Mickaël Pomes‐Hadda, Nathan J. Van Zee, Cédric Lorthioir, Clément Guibert, Guillaume Vives   +7 more
wiley   +1 more source

Transition-Metal Hydride Catalysis Meets Nitrenoid Transfer: Design Principles for Precision C-N Bond Formation. [PDF]

Acc Chem Res
Lyu X, Choi H, Chang S.
europepmc   +1 more source

Stereoselective Synthesis of β‐C‐glycosides From Exoglycals Through Radical C─C Bond Formation

Chemistry – A European Journal, EarlyView.
We describe herein a convenient strategy for the preparation of β‐C‐glycosides via the addition of radical species onto exoglycals. This method is efficient, general and achieved in mild conditions starting from xanthates derivatives and using triethylborane as initiator and 4‐tert‐butylcatechol as hydrogen atom source. This hydroalkylation reaction is
Noémie Murard, Guillaume Pilet, David Gueyrard   +2 more
wiley   +1 more source

Photochemical C4-Selective C-H Amination of Quinolines via <i>N</i>-Shift of Heteroaryl Azides. [PDF]

Org Lett
Dimasi A, Montoli A, Macetti G, Lo Presti L, Passarella D, Fasano V.   +5 more
europepmc   +1 more source

Halogenated Tryptophans Improve Integrin αVβ6 Affinity of Cyclic RGD Peptides and Provide Handles for Late‐Stage Derivatization

Chemistry – A European Journal, EarlyView.
Lighting up αVβ6: Halotryptophan engineering converts an RGD scaffold into a modular αVβ6 ligand platform, enabling picomolar affinity and late‐stage functionalization. The resulting probes combine high selectivity with fluorescence for FACS and tumor imaging.
Beate Nachtigall, Caroline Brinkmann, Jana Langosch, Anke Nieß, Norbert Sewald   +4 more
wiley   +1 more source

Catalytic [6 + 3] cycloaddition for the synthesis of medium-sized ring systems: a critical review. [PDF]

RSC Adv
Archna, Kumar G, Chawla PA, Kumar R, Bhargava G.   +4 more
europepmc   +1 more source