Results 201 to 210 of about 29,422 (294)

Nitric Oxide Tunes Secreted Metabolite Bioactivity

open access: yesMolecular Microbiology, EarlyView.
Pseudomonas aeruginosa produces phenazine metabolites that can react with nitric oxide (·NO) to form nitrosylated compounds. The formation of these metabolites results in rapid loss in P. aeruginosa viability and diminishes phenazine antimicrobial activity against other organisms, including Staphylococcus aureus. ABSTRACT The radical nitric oxide (·NO)
Zachery R. Lonergan   +7 more
wiley   +1 more source

Determinants of undesired α2-6-sialoside formation by PmST1 M144D. [PDF]

open access: yesOrg Biomol Chem
Mozaneh F   +4 more
europepmc   +1 more source

Structural Elucidation and Engineering of the (S)‐scoulerine 2‐O‐Methyltransferase Enabling Regioselective Epiberberine Biosynthesis in Coptis chinensis

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT Protoberberine alkaloids are a characteristic group of natural products in Coptis plants known for their notable pharmacological activities. However, the structural similarity and the substrate promiscuity of their biosynthetic enzymes have left the precise synthetic pathways remain unclarified, posing challenges to regulate product formation.
Jun Song   +14 more
wiley   +1 more source

Hydroxyaldehyde and formyl photoproducts of protoporphyrin IX formed under photodynamic diagnosis and therapy irradiation conditions

open access: yesPhotochemistry and Photobiology, EarlyView.
Photoproducts of the photosensitizer protoporphyrin IX (PpIX) may have diagnostic and therapeutic relevance in photodynamic diagnosis (PDD) and photodynamic therapy (PDT). These photoproducts possess fluorescence and photosensitizing properties and could serve as a complementary dosimetry index alongside photosensitizer photobleaching. The formation of
Sochi J. Ogbonna   +2 more
wiley   +1 more source

Photoinduced Copper‐Catalyzed para‐Selective C–H S‐Arylation of Benzylic Oxime Carbonates with Sulfenamides

open access: yesChinese Journal of Chemistry, Volume 44, Issue 13, Page 2160-2166, 1 July 2026.
We present a dual copper/photoredox catalytic system that enables the para‐selective C–H functionalization of benzyl alcohols with sulfenamides. This approach facilitates the para‐selective C–H sulfilimination of benzylic oxime carbonates through an orchestrated sequence involving photoinduced decarboxylation/dearomatization of oxime carbonates, copper‐
Sanhua Zhang   +4 more
wiley   +1 more source

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