Results 211 to 220 of about 37,566 (244)

Difluoromethylenation of Alkynes: Streamlined Access to Allyl Difluorides

Angewandte Chemie, Volume 138, Issue 46, 9 November 2026.
Stabilizing primary oxocarbenium in HF/pyridine unlocks a direct alkyne difluoromethylenation – an efficient route to synthetically‐relevant allyl difluorides in a single step. ABSTRACT A direct difluoromethylenation of alkynes has been developed using HF/pyridine as a dual acidic and fluorinating medium. The reaction proceeds via in situ generation of
Fabien Naullet, Sourav Mondal, Frédéric Guégan, Bastien Michelet, Sébastien Thibaudeau   +4 more
wiley   +2 more sources

Unveiling the Origin of Regioselectivity in Iron(III)-Promoted Friedel-Crafts Synthesis of Cannabinoids: Theoretical Studies and Synthetic Applications. [PDF]

J Org Chem
El Hllafi M, Cheng-Sánchez I, Fuentes-Pino I, Sánchez-Ruiz A, López-Romero JM, Suárez J, El Amrani MA, Sarabia F.   +7 more
europepmc   +1 more source

Cobalt‐Catalyzed [2σ+2π] Cycloaddition via Site‐Selective Capture of Bicyclobutane Diradical

Angewandte Chemie, Volume 138, Issue 46, 9 November 2026.
We report a Co(II)‐catalyzed strategy that combines thermal activation of bicyclo[1.1.0]butane (BCBs) with site‐selective radical capture to furnish head‐to‐head fused bicyclo[2.1.1]hexanes via [2σ+2π] cycloaddition with indoles. Detailed mechanistic studies (31P NMR, EPR, CV, and DFT) support the catalytic pathway, while phosphine‐oxide trapping and X‐
Tanmayee Nanda, Alexander Umanzor, Julia Gartzke, Jeremy T. Maddigan‐Wyatt, Philipp Thielert, Stefan Weber, Sabine Richert, Shuming Chen, Daniel B. Werz   +8 more
wiley   +2 more sources

Data-Driven Approach to Understanding Tetrabutylammonium Decatungstate-Catalyzed C(sp³)-H Functionalization Selectivity. [PDF]

Angew Chem Int Ed Engl
Lavin M, Tekle-Smith MA.
europepmc   +1 more source

Ligand-enabled palladium-catalyzed late-stage C-H fluorination of arenes. [PDF]

Chem Sci
Teja C, Islam M, Grover J, Bairagi Y, Sankar V, Pothikumar R, Yadav AK, Maiti D.   +7 more
europepmc   +1 more source

Regio- and Enantioselective Functionalization of Gaseous Alkanes via Nickel-Catalyzed Alkene Dicarbofunctionalization. [PDF]

J Am Chem Soc
Barbeira-Arán S, Nair AM, Malga JM, Hu X, Rentería-Gómez Á, Liu Y, Gogoi AR, Gutierrez O, Nevado C, Fañanás-Mastral M.   +9 more
europepmc   +1 more source

Regioselective Hydroboration of Terminal Alkenes with the Addition of Triflic Acid to Borane. [PDF]

J Org Chem
Fourati I, Woerpel KA.
europepmc   +1 more source

Scaffold hopping of furans into 3-cyanopyridines. [PDF]

Nat Commun
Kafle P, Yasuda S, Herndon D, Nilson D, Fox RC, Akhmedov NG, Sharma I.   +6 more
europepmc   +1 more source

Synthesis and diversification of SuFEx-active 2<i>H</i>-indazoles from azobenzenes and ethenesulfonyl fluoride. [PDF]

RSC Adv
Rajaka L, Woo H, Jung M, Jang C, Kim S, Lee J, Kim S, Han S, Bae HY, Han SH.   +9 more
europepmc   +1 more source

Rega: A Platform for the Prediction of the Regioselectivity of C-H Functionalization Reactions. [PDF]

J Chem Inf Model
Walton PJ, Tatin H, Baxter A, Ermanis K, Denton RM, Hirst JD.   +5 more
europepmc   +1 more source