Results 221 to 230 of about 29,422 (294)

Stereoselective Prenylation of Aryl- and Heteroaryl Halides: γ-Selective Suzuki-Miyaura Coupling as a Tool for Asymmetric Csp²-Csp³ Cross-Coupling. [PDF]

J Org Chem
Pawlowsky C, Leipertz T, Henßen B, Haase M, Pietruszka J.   +4 more
europepmc   +1 more source

Synthesis and Evaluation of Aromatic Sulfonamide and Disulfonamide Derivatives as Dengue Virus NS3–NS5 Interaction Inhibitors

ChemMedChem, Volume 21, Issue 11, 15 June 2026.
A synthetic methodology for the preparation of asymmetric benzene‐1,4‐disulfonamides was developed and applied to generate potential anti‐dengue virus (DENV) compounds. Guided by computer‐assisted structural rationalization, we designed synthetically more accessible analogs with reduced toxicity that interact with the DENV NS5 domain, thereby ...
Jakub Janáč, Jan Drahorád, Jakub Harvalík, Tereza Horáčková, Manfred Brinker, Arianna Loregian, Andrea Brancale, Beatrice Mercorelli, Petra Cuřínová   +8 more
wiley   +1 more source

Palladium-Catalyzed Enantioselective [4 + 2] Annulation with Allenes: Direct Access to Chiral Silatetralins. [PDF]

JACS Au
Zhou H, Sun Y, Xu R, Chen T, Gao L, Zhao G, Zhang J, Wang Y.   +7 more
europepmc   +1 more source

Mechanochemical SNAr on Phthalonitriles: Distinct Reactivity and Selectivity in One‐Pot Synthesis for Greener Phthalocyanines

ChemSusChem, Volume 19, Issue 11, 15 June 2026.
Mechanochemical nucleophilic aromatic substitution enables efficient, reproducible functionalization of phthalonitriles under minimal solvent conditions with high versatility. Integrating this process with solid‐state cyclotetramerization affords metalated and metal‐free phthalocyanines in a streamlined sustainable one‐pot workflow.
Obed Rodriguez‐Perez, Daniel Langerreiter, Sandra Kaabel, Eduardo Anaya‐Plaza   +3 more
wiley   +1 more source

N‐Glycosyl Triazoline Glycomimetics via Huisgen Cycloaddition With an Electron‐Deficient Alkene and BF3‐Catalysed Triazoline Fragmentation to Aziridines

European Journal of Organic Chemistry, Volume 29, Issue 22, 9 June 2026.
Glycomimetics with triazoline and aziridine groups were synthesised via diastereoselective Huisgen cycloaddition from glycosyl azides. Density functional theory was applied to define the mechanism for BF3 promoted aziridine formation. Triazoline and aziridine derivatives were synthesised by diastereo‐ and regioselective Huisgen cycloaddition of 2,3,4,6‐
Aaron McCormack, Ashis Dhara, Lamis Alaa Eldin Refat, Mikael Bols, Paul V. Murphy   +4 more
wiley   +1 more source

Engineering a cytochrome P450 enzyme as a peroxygenase for selective hydroxylation of steroids. [PDF]

Nat Commun
Tang T, Wang R, Chen Y.
europepmc   +1 more source

Electrophilic Iodination of Heterocyclic Compounds. Recent Advances 2008–2025: Part II

European Journal of Organic Chemistry, Volume 29, Issue 22, 9 June 2026.
Electrophilic iodination using molecular iodine and iodide sources represents an efficient approach for accessing valuable iodinated organic compounds. This review highlights recent advances in the iodination of heterocyclic compounds from 2008 to 2025, emphasizing the role of heteroaryl iodides as important synthetic intermediates for biologically ...
Njomza Ajvazi, Stojan Stavber
wiley   +1 more source

Pd-Catalyzed C─C Bond Borylation of Biphenylenes Leading to Tri-Ortho-Substituted Biaryls. [PDF]

Chemistry
Presland RV, Luzyanin KV, Wilkinson LA, Jacobs OL, Halcovitch NR, Sergeev AG.   +5 more
europepmc   +1 more source

Highly Cα-regio-, enantio- and diastereoselective Mukaiyama-type annulation of siloxyfurans: stereodivergent synthesis of multi-stereogenic tricyclic γ-lactones. [PDF]

Chem Sci
Gan L, Li ZQ, Chen T, Wan X, Zhang J, Ren J, Jiang M, Cao P, Huang J, Deng YH, Peng F, Tian R, Wang Y, Zhang Z, Shao Z.   +14 more
europepmc   +1 more source

Mechanistic Insights into the Regioselective (3 + 2) Cycloaddition of Unsymmetrical Cyclopropenones with Elemental Sulfur: Experimental and Computational Studies. [PDF]

J Org Chem
Rivero P, Nuñez GD, Miró E, Villares M, Carbó JJ, Castillón S, Díaz Y, Besora M, Matheu MI.   +8 more
europepmc   +1 more source