Results 221 to 230 of about 45,362 (276)

Stereochemical Dissection of the Strobilurin PKS Reveals the Complex Biosynthetic Logic of Iterative EZE Triene Construction

Angewandte Chemie International Edition, Volume 65, Issue 4, 22 January 2026.
The strobilurin iterative PKS assembles a remarkable EZE triene by varying its stereoselectivity during synthesis. Stereoselective 2R‐methylation of the triketide intermediate by the C‐terminal C‐methyltransferase domain induces the KR and DH domains to invert their native stereoselectivities and produce a Z‐configured intermediate.
Maurice Hauser, Jing Pang, Daowan Lai, Yunlong Sun, Hao Yao, Russell J. Cox   +5 more
wiley   +1 more source

Comprehensive engineering of novel glycosyltransferase for efficient, donor-promiscuous, and regioselective glycosylation of flavonoids. [PDF]

Sci Adv
Lu Y, Xie L, Xie J, Liu G, Fu J, Zou L, Lin Q, Wang Y, Chen W.   +8 more
europepmc   +1 more source

Regioselective access to B–N Lewis pair-functionalized anthracenes: mechanistic studies and optoelectronic properties

Jingyao Zuo, Roger A. Lalancette, Demyan E. Prokopchuk, Frieder Jaekle   +3 more
openalex   +2 more sources

Iridium(III)-catalyzed remote B(9)-H alkylation of o-carboranes with nitrile template. [PDF]

Nat Commun
Lee K, Kim J, Hwang D, Yang B, Kang D, Kim D, Baik MH, Lee PH.   +7 more
europepmc   +1 more source

Lewis Acid-Catalyzed Divergent (4+3)/(4+2) Annulations of <i>o</i>-Quinone Methides with Bicyclo[1.1.0]butanes Lead to sp³-Rich Oxabicyclic Frameworks. [PDF]

Org Lett
Mondal S, Patel M, Hazra S, Hajra S, Saha J.   +4 more
europepmc   +1 more source

Advances in hydroformylation with formaldehyde, formic acid and carbon dioxide as syngas surrogates. [PDF]

RSC Adv
Zhao Z, Lei S, Feng W, Wang X, Li H, Chen H, Wang L, Zhao F, Fu S.   +8 more
europepmc   +1 more source

Enantioselective Syntheses of Secondary Alkylboronates via Asymmetric Regioselective Reduction of 1,3‐Dienylboronates

Angewandte Chemie, Volume 138, Issue 3, 16 January 2026.
We report herein the development of catalytic asymmetric synthesis of secondary alkyl boronates. Under the optimal conditions, Cu‐catalyzed semi‐reduction of 1‐alkyl‐ or 1,3‐dialkyl‐substituted 1‐boryl‐1,3‐butadienes forms secondary alkyl boronates with excellent regioselectivities and enantioselectivities.
Wen‐Bin Cao, Lingfei Hu, Jiaming Liu, George Chen, Gang Lu, Ming Chen   +5 more
wiley   +1 more source

Pericyclic Umpolung in a Catalytic Asymmetric Diels-Alder Reaction of Tropone with Enol Ethers. [PDF]

J Am Chem Soc
Zheng T, Wang Z, Mitschke B, Nöthling N, Leutzsch M, Neese F, List B.   +6 more
europepmc   +1 more source

Design, Synthesis, and Structural Evolution of Pseudo‐Natural Product IDO1 Inhibitors and Degraders

Angewandte Chemie, Volume 138, Issue 3, 16 January 2026.
The combination of bicyclic monoterpene‐ and pyrrolidine‐alkaloid fragments yields novel pseudo‐natural products. Biological characterization revealed that these iDegs are inhibitors and degraders of indoleamine‐2,3‐dioxygenase. Abstract Terpenoid alkaloids are derived from the fusion of structurally diverse terpenoid‐ and alkaloid moieties.
Xiu‐Fen Cheng, Belén Lucas, Philipp Lampe, Stefano Ugel, Suyuan Chen, Anke Unger, Matthias Bischoff, Soheila Rezaei Adariani, Kesava Reddy Naredla, Kamal Kumar, Annika Schmidt, Carsten Strohmann, Petra Janning, Raphael Gasper, María Lucas, Malte Gersch, Sonja Sievers, Vincenzo Bronte, Slava Ziegler, Herbert Waldmann   +19 more
wiley   +1 more source

Elucidating Ligand-Dependent Selectivities in Pd-Catalyzed C-H Activations. [PDF]

Angew Chem Int Ed Engl
Deufel F, Ravi M, van Gemmeren M.
europepmc   +1 more source