Results 71 to 80 of about 45,362 (276)

Catalytic Hydrothiolation: Counterion-Controlled Regioselectivity [PDF]

Journal of the American Chemical Society, 2019
In this Article, we expand upon the catalytic hydrothiolation of 1,3-dienes to afford either allylic or homoallylic sulfides with high regiocontrol. Mechanistic studies support a pathway in which regioselectivity is dictated by the choice of counterion associated with the Rh center.
Xiao-Hui Yang, Ryan T. Davison, Shao-Zhen Nie, Faben A. Cruz, Tristan M. McGinnis, Vy M. Dong   +5 more
openaire   +4 more sources

A Precisely Bromo‐Functionalized [9]Cycloparaphenylene as a Platform for Late‐Stage Multisite π‐Extension Toward Chiral Nanohoops

Angewandte Chemie, EarlyView.
Precisely synthesized hexabrominated [9]cycloparaphenylene (CPP), accessed by a gold‐mediated method, enables efficient multisite post‐functionalization through cross‐coupling reactions. Late‐stage π‐extension on the CPP framework successfully affords armchair‐type chiral nanohoops exhibiting strong circularly polarized luminescence (|glum| = 0.100 ...
Naoya Kinoshita, Nanami Kotani, Masaya Sugiura, Kotaro Matsumura, Daisuke Sakamaki, Daiki Tauchi, Masashi Hasegawa, Hidetoshi Kawai, Yoshitaka Tsuchido   +8 more
wiley   +2 more sources

Chlorine Isotope Effects from Isotope Ratio Mass Spectrometry Suggest Intramolecular C-Cl Bond Competition in Trichloroethene (TCE) Reductive Dehalogenation

Molecules, 2014
Chlorinated ethenes are prevalent groundwater contaminants. To better constrain (bio)chemical reaction mechanisms of reductive dechlorination, the position-specificity of reductive trichloroethene (TCE) dehalogenation was investigated.
Stefan Cretnik, Anat Bernstein, Orfan Shouakar-Stash, Frank Löffler, Martin Elsner   +4 more
doaj   +1 more source

Pyridine Into Pyrrole Transformation Induced Within the Confinement of the Macrocycle

Angewandte Chemie, EarlyView.
This work demonstrates the nontrivial reactivity of pyridine incorporated into a porphyrin framework. The most significant achievement is the contraction of the six‐membered ring to a pyrrole ring, which is a phenomenon of great interest to researchers in this field.
Paulina Krzyszowska, Agata Burska‐Jabłońska, Mateusz Oberski, Michał J. Białek, Lechosław Latos‐Grażyński, Karolina Hurej   +5 more
wiley   +2 more sources

A Stereocontrolled Protocol to Highly Functionalized Fluorinated Scaffolds through a Fluoride Opening of Oxiranes

Molecules, 2016
A novel selective and substrate-dependent synthetic protocol has been developed towards the synthesis of various fluorine-containing, highly functionalized cycloalkane derivatives.
Attila Márió Remete, Melinda Nonn, Santos Fustero, Ferenc Fülöp, Loránd Kiss   +4 more
doaj   +1 more source

Total Synthesis of (+)‐Melonine and (+)‐N4‐Oxy Melonine Enabled by an Intramolecular Alkene Diamination Reaction

Angewandte Chemie, EarlyView.
A complexity‐generating intramolecular alkene diamination constitutes the pivotal step in the enantioselective synthesis of the title natural products featuring a strained, cage‐like pentacyclic architecture. Abstract Among more than four thousand monoterpene indole alkaloids (MIAs) isolated to date, only a few feature a 2,2,3‐trisubstituted indoline ...
Vincent Goëlo, Qian Wang, Jieping Zhu
wiley   +2 more sources

Catalyst‐Free Regioselective Diborylation of Aryllithium with Tetra(o‐tolyl)diborane(4) [PDF]

, 2023
Xiaofeng Mao, Zhenpin Lu, Jie Zhang, Zuowei Xie   +3 more
openalex   +1 more source

Ligand control of regioselectivity in palladium-catalyzed heteroannulation reactions of 1,3-Dienes

Nature Communications
Olefin carbofunctionalization reactions are indispensable tools for constructing diverse, functionalized scaffolds from simple starting materials. However, achieving precise control over regioselectivity in intermolecular reactions remains a formidable ...
Dasha Rodina, Jakub Vaith, Shauna M. Paradine   +2 more
doaj   +1 more source

Regioselectivity of H Cluster Oxidation

Journal of the American Chemical Society, 2011
The H(2)-evolving potential of [FeFe] hydrogenases is severely limited by the oxygen sensitivity of this class of enzymes. Recent experimental studies on hydrogenase from C. reinhardtii point to O(2)-induced structural changes in the [Fe(4)S(4)] subsite of the H cluster. Here, we investigate the mechanistic basis of this observation by means of density
Bruska, Marta K., Stiebritz, Martin T., Reiher, Markus   +2 more
openaire   +2 more sources

Stereoselective epoxidation of the last double bond of polyunsaturated fatty acids by human cytochromes P450

Journal of Lipid Research, 2010
Cytochromes P450 (CYPs) metabolize polyunsaturated long-chain fatty acids (PUFA-LC) to several classes of oxygenated metabolites. Through use of human recombinant CYPs, we recently showed that CYP1A1, -2C19, -2D6, -2E1, and -3A4 are mainly hydroxylases ...
Danièle Lucas, Sophie Goulitquer, Jan Marienhagen, Maude Fer, Yvonne Dreano, Ulrich Schwaneberg, Yolande Amet, Laurent Corcos   +7 more
doaj   +1 more source