Results 91 to 100 of about 343,210 (289)

Immunosuppressive therapy in patients with biopsy-proven inflammatory myocardial disease: a systematic review and meta-analysis

Scientific Reports
The aim of this study was to evaluate and update the effects of immunosuppressive therapy on heart failure outcomes in patients aged 16 years or older with biopsy-proven inflammatory myocardial disease.
Bruno Stautner, Michał Tkaczyszyn, Anne Sorg, Tomasz Suchocki, Ewa Anita Jankowska   +4 more
doaj   +1 more source

Establishing a Multi-Country Sickle Cell Disease Registry in Africa: Ethical Considerations

Frontiers in Genetics, 2019
Sickle cell disease (SCD) is one of the most prevalent genetic conditions in sub-Saharan Africa. It is a chronic, lifelong disease often characterized by severe pain.
Nchangwi Syntia Munung, Nchangwi Syntia Munung, Victoria Nembaware, Victoria Nembaware, Jantina de Vries, Daima Bukini, Furahini Tluway, Marsha Treadwell, Marsha Treadwell, Raphael Zozimus Sangeda, Raphael Zozimus Sangeda, Gaston Mazandu, Gaston Mazandu, Mario Jonas, Mario Jonas, Vivian Paintsil, Obiageli E. Nnodu, Emmanuel Balandya, Julie Makani, Ambroise Wonkam, Ambroise Wonkam   +20 more
doaj   +1 more source

[Prognosis of colorectal cancer and socio-economic inequalities].

, 2006
It is well established that socio-economic status is a major prognostic factor for many cancers, including colorectal cancer. The aims of this review are (i) to report epidemiological data showing how socio-economic status influences colorectal cancer ...
Mitry, Emmanuel, Rachet, Bernard
core   +1 more source

Lessons Learned From a Delayed‐Start Trial of Modafinil for Freezing of Gait in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Freezing of gait (FOG) in people with Parkinson's disease (PwPD) is debilitating and has limited treatments. Modafinil modulates beta/gamma band activity in the pedunculopontine nucleus (PPN), like PPN deep brain stimulation. We therefore tested the hypothesis that Modafinil would improve FOG in PwPD.
Tuhin Virmani, Lakshmi Pillai, Reid D. Landes, Aliyah Glover, Shannon Doerhoff, Jennifer Kleiner, Mitesh Lotia, Rohit Dhall, Edgar Garcia‐Rill   +8 more
wiley   +1 more source

Electronic titling: Potential and risks [PDF]

Initiatives in electronic conveyancing and registration show the potential of new technologies to transform such systems, reducing costs and enhancing legal security.
Benito Arruñada
core  

Predicting Epileptogenic Tubers in Patients With Tuberous Sclerosis Complex Using a Fusion Model Integrating Lesion Network Mapping and Machine Learning

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Accurate localization of epileptogenic tubers (ETs) in patients with tuberous sclerosis complex (TSC) is essential but challenging, as these tubers lack distinct pathological or genetic markers to differentiate them from other cortical tubers.
Tinghong Liu, Qi Wang, Suhui Kuang, Dezhi Cao, Ping Ding, Shaohui Zhang, Haihua Wei, Zhirong Wei, Jinshan Xu, Xinyu Huang, Bing Liu, Shuli Liang   +11 more
wiley   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

ALS With and Without Upper Motor Neuron Signs: A Comparative Study Supporting the Gold Coast Criteria

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The Gold Coast criteria permit diagnosis of amyotrophic lateral sclerosis (ALS) even without upper motor neuron (UMN) signs. However, whether ALS patients with UMN signs (ALSwUMN) and those without (ALSwoUMN) share similar characteristics and prognoses remains unclear.
Hee‐Jae Jung, E‐nae Cheong, Jungmin So, Heung‐Won Kang, Yangsean Choi, Eun‐Jae Lee, Hyunjin Kim, Young‐Min Lim   +7 more
wiley   +1 more source

Development and Validation of a Minimum Dataset for a Pediatric Septic Shock Registry: A Descriptive and Cross‐Sectional Study

Health Science Reports
Background and Aims Septic shock is the most severe form of sepsis in children, characterized by circulatory problems, cellular and metabolic damage, and a high risk of mortality. Managing data through a registry can enhance care and treatment follow‐up.
Fariba Shabani, Seyedeh Narjes Ahmadizadeh, Shahabedin Rahmatizadeh, Seyedeh Masumeh Hashemi, Reza Rabiei, Azita Behzad   +5 more
doaj   +1 more source

Sometimes the Silence Can Be like the Thunder: Access to Pharmaceutical Data at the FDA [PDF]

, 2006
Those committed to the free exchange of scientific information have long complained about various restrictions on access to the FDA\u27s pharmaceutical data and the resultant restrictions on open discourse.
Lurie, Peter, Zieve, Allison
core   +1 more source