Results 71 to 80 of about 3,894,475 (297)

Predicting Crash Rate Using Logistic Quantile Regression With Bounded Outcomes

IEEE Access, 2017
Various approaches and perspectives have been presented in safety analysis during the last decade, but when some continuous outcome variables take on values within a bounded interval, the conventional statistical methods may be inadequate, and frequency ...
Xuecai Xu, Li Duan
doaj   +1 more source

Minimax Rate of Testing in Sparse Linear Regression [PDF]

Automation and Remote Control, 2019
We consider the problem of testing the hypothesis that the parameter of linear regression model is 0 against an s-sparse alternative separated from 0 in the l2-distance. We show that, in Gaussian linear regression model with p < n, where p is the dimension of the parameter and n is the sample size, the non-asymptotic minimax rate of testing has the ...
Carpentier, Alexandra, Collier, Olivier, Comminges, Laëtitia, Tsybakov, Alexandre, Wang, Yuhao   +4 more
openaire   +4 more sources

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

Regularity dependence of the rate of convergence of the learning curve for Gaussian process regression [PDF]

, 2012
This paper deals with the speed of convergence of the learning curve in a Gaussian process regression framework. The learning curve describes the average generalization error of the Gaussian process used for the regression.
Garnier, Josselin, Gratiet, Loic Le
core   +2 more sources

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source

Approaches to Low Fuel Regression Rate in Hybrid Rocket Engines

International Journal of Aerospace Engineering, 2012
Hybrid rocket engines are promising propulsion systems which present appealing features such as safety, low cost, and environmental friendliness. On the other hand, certain issues hamper the development hoped for.
Dario Pastrone
doaj   +1 more source

Direct regression models for longitudinal rates of change [PDF]

Statistics in Medicine, 2014
Comparing rates of growth, or rates of change, across covariate‐defined subgroups is a primary objective for many longitudinal studies. In the special case of a linear trend over time, the interaction between a covariate and time will characterize differences in longitudinal rates of change.
Bryan, Matthew, Heagerty, Patrick J.
openaire   +2 more sources

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Regression Models and Fuzzy Logic Prediction of TBM Penetration Rate

Open Engineering, 2017
This paper presents statistical analyses of rock engineering properties and the measured penetration rate of tunnel boring machine (TBM) based on the data of an actual project.
Minh Vu Trieu, Katushin Dmitri, Antonov Maksim, Veinthal Renno   +3 more
doaj   +1 more source

Robust Estimation of High-Dimensional Mean Regression [PDF]

, 2014
Data subject to heavy-tailed errors are commonly encountered in various scientific fields, especially in the modern era with explosion of massive data.
Fan, Jianqing, Li, Quefeng, Wang, Yuyan
core