Results 71 to 80 of about 2,020,990 (315)

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

DATA-DRIVEN RATE-OPTIMAL SPECIFICATION TESTING IN REGRESSION MODELS [PDF]

open access: yes
We propose new data-driven smooth tests for a parametric regression function. The smoothing parameter is selected through a new criterion that favors a large smoothing parameter under the null hypothesis.
Emmanuel Guerre, Pascal Lavergne
core  

Support vector regression for warranty claim forecasting [PDF]

open access: yes, 2011
Forecasting the number of warranty claims is vitally important for manufacturers/warranty providers in preparing fiscal plans. In existing literature, a number of techniques such as log-linear Poisson models, Kalman filter, time series models, and ...
Akbarov, Artur   +3 more
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Least squares estimation of regression coefficients of singular random fields observed on a sphere

open access: yes, 2001
We present some results on the rate of convergence to the normal law of the least square estimates of the regression coefficient of random fields with long range dependence observed on a ...
Anh, Vo   +5 more
core  

Predictive distribution of regression vector and residual sum of squares for normal multiple regression model [PDF]

open access: yes, 2004
This paper proposes predictive inference for the multiple regression model with independent normal errors. The distributions of the sample regression vector (SRV) and the residual sum of squares (RSS) for the model are derived by using invariant ...
Shahjahan Khan, Khan, Shahjahan
core   +1 more source

Prediction of the breast cancer mortality rate and its effective factors using genetic algorithm and logistic regression

open access: yes, 2022
Introduction: Logistic regression is one of the most common models used to predict and classify binary and multiple state responses in medicine. Genetic algorithms search techniques inspired by biology have recently been used successfully as a predictive
Mirzaie, M   +5 more
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

The Effect of Exchange Rate Movements on Heterogeneous Plants: A Quantile Regression Analysis [PDF]

open access: yes
In this paper, we examine how the effect of movements in the real exchange rate on manufacturing plants depends on the plant’s placement within the productivity distribution.
Ben Tomlin, Loretta Fung
core  

A spectral algorithm for robust regression with subgaussian rates

open access: yesCoRR, 2020
We study a new linear up to quadratic time algorithm for linear regression in the absence of strong assumptions on the underlying distributions of samples, and in the presence of outliers. The goal is to design a procedure which comes with actual working code that attains the optimal sub-gaussian error bound even though the data have only finite ...
openaire   +2 more sources

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