Results 131 to 140 of about 1,659,012 (319)

Role of Activating Protein-1 in the Regulation of the Vascular Cell Adhesion Molecule-1 Gene Expression by Tumor Necrosis Factor-α [PDF]

, 1998
Mushtaq Ahmad, Pandora Theofanidis, Russell M. Medford   +2 more
openalex   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Regulation of xanthine dehydrogenase and xanthine oxidase activity and gene expression in cultured rat pulmonary endothelial cells. [PDF]

, 1992
Grégoire Dupont, Tom Huecksteadt, Bruce C. Marshall, Una Ryan, J R Michael, John R. Hoidal   +5 more
openalex   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Human chondrocyte culture models for studying cyclooxygenase expression and prostaglandin regulation of collagen gene expression

, 1999
MB Goldring, Francis Bérenbaum
openalex   +1 more source

TREVI ^XMBD : A Transcriptional Regulation-driven Variational Inference Model to Speculate Gene Expression Mechanism with Integration of Single-cell Multi-omics [PDF]

, 2023
Lan Cao, Wenhao Zhang, Feng Zeng, Ying Wang   +3 more
openalex   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Plant nuclear envelope as a hub connecting genome organization with regulation of gene expression. [PDF]

Nucleus, 2023
Tang Y.
europepmc   +1 more source

Transcriptional regulation of glutamine synthetase gene expression by dexamethasone in L6 muscle cells.

, 1990
Bo Feng, Dana Hilt, S. R. Max
openalex   +1 more source

PTRcombiner: mining combinatorial regulation of gene expression from post-transcriptional interaction maps [PDF]

, 2014
Gianluca Corrado, Toma Tebaldi, Giulio Bertamini, Fabrizio Costa, Alessandro Quattrone, Gabriella Viero, Andrea Passerini   +6 more
openalex   +1 more source