Results 51 to 60 of about 1,600,466 (167)
The Tumor Suppressor ARID1A Controls Global Transcription via Pausing of RNA Polymerase II
Cell Reports, 2018 Summary: AT-rich interactive domain-containing proteins 1A and 1B (ARID1A and ARID1B) are mutually exclusive subunits of the chromatin remodeler SWI/SNF. ARID1A is the most frequently mutated chromatin regulator across all cancers, and ovarian clear cell
Marco Trizzino +8 more
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Cells, 2019 Human rDNA clusters form numerous contacts with different chromosomal regions as evidenced by chromosome conformation capture data. Heterochromatization of rDNA genes leads to heterochromatization in different chromosomal regions coupled with the ...
Nickolai A. Tchurikov +6 more
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Regulation of Tobamovirus Gene Expression
, 1990 This chapter discusses tobacco mosaic virus (TMV) strains U1, OM, L, CGMMV, 0, and Cc. The production of each TMV protein is regulated differently, both in amounts and times of production. The chapter discusses some of the strategies that tobamoviruses uses to control gene expression: (1) different subgenomic RNA promoter/leader sequences control ...
William O. Dawson, Kirsi Lehto
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ZEB1 protects skeletal muscle from damage and is required for its regeneration
Nature Communications, 2019 Following muscle damage, an inflammatory response is associated to activation of satellite cells, which drive muscle repair. Here, the authors show that upregulation of Zeb1 in macrophages and muscle fibres regulates inflammation, and also show a role ...
Laura Siles +4 more
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eLife, 2017 We have identified the plant biflavonoid hinokiflavone as an inhibitor of splicing in vitro and modulator of alternative splicing in cells. Chemical synthesis confirms hinokiflavone is the active molecule.
Andrea Pawellek +8 more
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An emergency brake for protein synthesis
eLife, 2017 The integrated stress response is able to rapidly shut down the synthesis of proteins in eukaryotic cells.
Vladislava Hronová +1 more
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Nature Communications, 2021 A Correction to this paper has been published: https://doi.org/10.1038/s41467-021-20927-9.
Keito Okazaki +20 more
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Redox Biology, 2020 Saliva plays an essential role in the maintenance of oral health. The oral cavity environment changes during aging mainly due to alterations in the secretion and composition of saliva.
Sisca Meida Wati +2 more
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Auxin-regulated gene expression
Philosophical Transactions of the Royal Society of London. B, Biological Sciences, 1986 During the 1960s a wide range of studies provided an information base that led to the suggestion that auxin-regulated cell processes - especially cell elongation - may be mediated by auxin-regulated gene expression. Indirect evidence from our work, based on the influence of inhibitors of RNA synthesis (e.g.
Ronald T. Nagao +7 more
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KDM2 Family Members are Regulated by HIF-1 in Hypoxia
Cells, 2017 Hypoxia is not only a developmental cue but also a stress and pathological stimulus in many human diseases. The response to hypoxia at the cellular level relies on the activity of the transcription factor family, hypoxia inducible factor (HIF).
Michael Batie +3 more
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