Results 1 to 10 of about 303,937 (307)

Regulation of viral replication by host restriction factors [PDF]

Frontiers in Immunology
Viral infectious diseases, caused by numerous viruses including severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), influenza A virus (IAV), enterovirus (EV), human immunodeficiency virus (HIV), hepatitis B virus (HBV), and human papillomavirus
Ying Lin, Ying Lin, Ying Lin, Yun Zhu, Yun Zhu, Ling Jing, Ling Jing, Ling Jing, Xiaobo Lei, Xiaobo Lei, Zhengde Xie, Zhengde Xie   +11 more
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SUMOylation in Viral Replication and Antiviral Defense

Advanced Science, 2022
SUMOylation is a ubiquitination‐like post‐translational modification that plays an essential role in the regulation of protein function. Recent studies have shown that proteins from both RNA and DNA virus families can be modified by SUMO conjugation ...
Yao Fan, Xiang Li, Lei Zhang, Zhi Zong, Fangwei Wang, Jun Huang, Linghui Zeng, Chong Zhang, Haiyan Yan, Long Zhang, Fangfang Zhou   +10 more
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Defining the minimal components of the influenza A virus replication machinery via an in vitro reconstitution system.

PLoS Biology, 2023
During influenza A virus infection, the viral RNA polymerase transcribes the viral negative-sense segmented RNA genome and replicates it in a two-step process via complementary RNA within viral ribonucleoprotein (vRNP) complexes. While numerous viral and
Zihan Zhu, Haitian Fan, Ervin Fodor
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Ubiquitination is required for effective replication of coxsackievirus B3. [PDF]

PLoS ONE, 2008
BACKGROUND: Protein ubiquitination and/or degradation by the ubiquitin/proteasome system (UPS) have been recognized as critical mechanisms in the regulation of numerous essential cellular functions.
Xiaoning Si, Guang Gao, Jerry Wong, Yahong Wang, Jingchun Zhang, Honglin Luo   +5 more
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Zika virus promotes CCN1 expression via the CaMKIIα-CREB pathway in astrocytes. [PDF]

, 2020
Zika virus (ZIKV) infection in the human central nervous system (CNS) causes Guillain-Barre syndrome, cerebellum deformity, and other diseases. Astrocytes are immune response cells in the CNS and an important component of the blood-brain barrier ...
Hu, Q, Ke, X, Li, P, Liu, Y, Mao, P, Sun, J, Tan, Z, Tang, Y, Wang, H, Zhang, W, Zhang, Y, Zheng, C, Zheng, Z   +12 more
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Replication and virus-induced transcriptome of HAdV-5 in normal host cells versus cancer cells--differences of relevance for adenoviral oncolysis. [PDF]

PLoS ONE, 2011
Adenoviruses (Ads), especially HAdV-5, have been genetically equipped with tumor-restricted replication potential to enable applications in oncolytic cancer therapy.
Dominik E Dorer, Frank Holtrup, Kurt Fellenberg, Johanna K Kaufmann, Sarah Engelhardt, Jörg D Hoheisel, Dirk M Nettelbeck   +6 more
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Pre- and Post-Transcriptional Control of HBV Gene Expression: The Road Traveled towards the New Paradigm of HBx, Its Isoforms, and Their Diverse Functions

Biomedicines, 2023
Hepatitis B virus (HBV) is an enveloped DNA human virus belonging to the Hepadnaviridae family. Perhaps its main distinguishable characteristic is the replication of its genome through a reverse transcription process. The HBV circular genome encodes only
Rodrigo A. Villanueva, Alejandra Loyola
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Inhibition of eIF2α Phosphorylation by Peste des Petits Ruminant Virus Phosphoprotein Facilitates Viral Replication

Frontiers in Veterinary Science, 2021
Peste des petits ruminant virus (PPRV) causes a highly contagious disease in small ruminants. The molecular mechanism of PPRV replication and its interactions with hosts are poorly studied.
Niyokwishimira Alfred, Niyokwishimira Alfred, Bang Qian, Xiaodong Qin, Xiangping Yin, Meera Prajapati, Meera Prajapati, Yongxi Dou, Yanmin Li, Zhidong Zhang   +9 more
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Epstein-Barr virus transcription factor Zta acts through distal regulatory elements to directly control cellular gene expression [PDF]

, 2015
Lytic replication of the human gamma herpes virus Epstein-Barr virus (EBV) is an essential prerequisite for the spread of the virus. Differential regulation of a limited number of cellular genes has been reported in B-cells during the viral lytic ...
Alison J. Sinclair, Anja Godfrey, Bailey, Bark-Jones, Beatty, Ben-Bassat, Bergbauer, Bhende, Bhende, Broderick, Carey, Chang, Chi, Farnham, Feederle, Feng, Flemington, Flower, Gentleman, Gordon Peters, Grabherr, Gupta, Gustems, Halder, Harshil Patel, Heather, Hollyoake, Hsu, Huang da, Huang da, Ijiel B. Naranjo Perez-Fernandez, Inman, Israel, Jiang, Jianmin Zuo, Kalla, Kalla, Kay Osborn, Kenney, Kenney, Klug, Krig, Kuppers, Li, Lieberman, Lieberman, Lieberman, Longnecker, Ma, Machanick, Martin Rowe, McClellan, Miller, Molyneux, Nicolae Balan, Pruitt, Rajaei Al-Mohammad, Ramasubramanyan, Ramasubramanyan, Richard G. Jenner, Rickinson, Rowe, Rowe, Scacheri, Shannon-Lowe, Sharada Ramasubramanyan, Takada, Thorvaldsdottir, Tsai, Tsang, Vetsika, Whyte, Yang, Young, Young, Yuan, Zuo, Zuo   +77 more
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Role of the Guanine Nucleotide Exchange Factor GBF1 in the Replication of RNA Viruses

Viruses, 2020
The guanine nucleotide exchange factor GBF1 is a well-known factor that can activate different ADP-ribosylation factor (Arf) proteins during the regulation of different cellular vesicular transport processes.
José L. Martínez, Carlos F. Arias
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