Results 21 to 30 of about 186,764 (256)
TRIM62 From Chicken as a Negative Regulator of Reticuloendotheliosis Virus Replication
Frontiers in Veterinary Science, 2020 Emerging evidence suggests that the tripartite motif containing 62 (TRIM62), a member of the TRIM family, plays an important role in antiviral processes.
Ling Li +6 more
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Hepatocyte nuclear factor 1α downregulates HBV gene expression and replication by activating the NF-κB signaling pathway. [PDF]
PLoS ONE, 2017 The role of hepatocyte nuclear factor 1α (HNF1α) in the regulation of gene expression and replication of hepatitis B virus (HBV) is not fully understood.
Junyu Lin +8 more
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TMP269, a small molecule inhibitor of class IIa HDAC, suppresses RABV replication in vitro
Frontiers in Microbiology, 2023 TMP269, a small molecular inhibitor of IIa histone deacetylase, plays a vital role in cancer therapeutic. However, the effect of TMP269 on the regulation of viral replication has not been studied.
Juanbin Yin +8 more
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Veterinary Research, 2021 Elucidating virus-cell interactions is fundamental to understanding viral replication and identifying targets for therapeutic control of viral infection.
Huan Wang +9 more
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Microbiology Spectrum, 2021 Upon Kaposi’s Sarcoma-associated herpesvirus (KSHV) lytic reactivation, rapid and widespread amplification of viral DNA (vDNA) triggers significant nuclear reorganization.
D. Hoffman +4 more
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Viral precursor polyproteins: keys of regulation from replication to maturation
Current Opinion in Virology, 2013 Many viruses use a replication strategy involving the translation of a large polyprotein, which is cleaved by viral and/or cellular proteases. Several of these viruses severely impact human health around the globe, including HIV, HCV, Dengue virus, and West Nile virus.
Yost, Samantha A, Marcotrigiano, Joseph
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A conformational switch at the 3′ end of a plant virus RNA regulates viral replication [PDF]
The EMBO Journal, 1999 3' untranslated regions of alfamo- and ilar-virus RNAs fold into a series of stem-loop structures to which the coat protein binds with high affinity. This binding plays a role in initiation of infection ('genome activation') and has been thought to substitute for a tRNA-like structure that is found at the 3' termini of related plant viruses. We propose
Olsthoorn, R.R.C.L. +3 more
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Virologica Sinica, 2022 The hepatitis B virus (HBV) is a global public health challenge due to its highly contagious nature. It is estimated that almost 300 million people live with chronic HBV infection annually. Although nucleoside analogs markedly reduce the risk of liver disease progression, the analogs do not fully eradicate the virus.
Xinna Ma +8 more
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HIV-1 gene expression: lessons from provirus and non-integrated DNA
Retrovirology, 2004 Replication of HIV-1 involves a series of obligatory steps such as reverse transcription of the viral RNA genome into double-stranded DNA, and subsequent integration of the DNA into the human chromatin.
Wu Yuntao
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Cellular and Viral Factors Regulating Merkel Cell Polyomavirus Replication
PLoS ONE, 2011 Merkel cell polyomavirus (MCV), a previously unrecognized component of the human viral skin flora, was discovered as a mutated and clonally-integrated virus inserted into Merkel cell carcinoma (MCC) genomes. We reconstructed a replicating MCV clone (MCV-HF), and then mutated viral sites required for replication or interaction with cellular proteins to ...
Feng, H +6 more
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