Results 31 to 40 of about 166,267,164 (196)
TRIM62 From Chicken as a Negative Regulator of Reticuloendotheliosis Virus Replication
Frontiers in Veterinary Science, 2020 Emerging evidence suggests that the tripartite motif containing 62 (TRIM62), a member of the TRIM family, plays an important role in antiviral processes.
Ling Li +6 more
doaj +1 more source
TMP269, a small molecule inhibitor of class IIa HDAC, suppresses RABV replication in vitro
Frontiers in Microbiology, 2023 TMP269, a small molecular inhibitor of IIa histone deacetylase, plays a vital role in cancer therapeutic. However, the effect of TMP269 on the regulation of viral replication has not been studied.
Juanbin Yin +8 more
doaj +1 more source
Virologica Sinica, 2022 The hepatitis B virus (HBV) is a global public health challenge due to its highly contagious nature. It is estimated that almost 300 million people live with chronic HBV infection annually. Although nucleoside analogs markedly reduce the risk of liver disease progression, the analogs do not fully eradicate the virus.
Xinna Ma +8 more
openaire +2 more sources
The multifunctional NS1 protein of influenza A viruses [PDF]
, 2012 The non-structural (NS1) protein of influenza A viruses is a non-essential virulence factor that has multiple accessory functions during viral infection.
Hale, Benjamin Geoffrey +3 more
core +2 more sources
Veterinary Research, 2021 Elucidating virus-cell interactions is fundamental to understanding viral replication and identifying targets for therapeutic control of viral infection.
Huan Wang +9 more
doaj +1 more source
Microbiology Spectrum, 2021 Upon Kaposi’s Sarcoma-associated herpesvirus (KSHV) lytic reactivation, rapid and widespread amplification of viral DNA (vDNA) triggers significant nuclear reorganization.
D. Hoffman +4 more
doaj +1 more source
A conformational switch at the 3′ end of a plant virus RNA regulates viral replication [PDF]
The EMBO Journal, 1999 3' untranslated regions of alfamo- and ilar-virus RNAs fold into a series of stem-loop structures to which the coat protein binds with high affinity. This binding plays a role in initiation of infection ('genome activation') and has been thought to substitute for a tRNA-like structure that is found at the 3' termini of related plant viruses. We propose
Olsthoorn, R.R.C.L. +3 more
openaire +3 more sources
NEDDylation is essential for Kaposi's sarcoma-associated herpesvirus latency and lytic reactivation and represents a novel anti-KSHV target. [PDF]
, 2015 Kaposi's sarcoma-associated herpesvirus (KSHV) is the causative agent of Kaposi's sarcoma (KS) and primary effusion lymphoma (PEL), which are aggressive malignancies associated with immunocompromised patients.
Wood, Jennifer J +19 more
core +1 more source
HIV-1 gene expression: lessons from provirus and non-integrated DNA
Retrovirology, 2004 Replication of HIV-1 involves a series of obligatory steps such as reverse transcription of the viral RNA genome into double-stranded DNA, and subsequent integration of the DNA into the human chromatin.
Wu Yuntao
doaj +1 more source
Viral precursor polyproteins: keys of regulation from replication to maturation
Current Opinion in Virology, 2013 Many viruses use a replication strategy involving the translation of a large polyprotein, which is cleaved by viral and/or cellular proteases. Several of these viruses severely impact human health around the globe, including HIV, HCV, Dengue virus, and West Nile virus.
Yost, Samantha A, Marcotrigiano, Joseph
openaire +2 more sources