Results 101 to 110 of about 29,276,589 (300)

A compilation of reports of the Advisory Committee on Reactor Safeguards, 1997 annual, U.S. Nuclear Regulatory Commission. Volume 19 [PDF]

, 1998
This compilation contains 67 ACRS reports submitted to the Commission, or to the Executive Director for Operations, during calendar year 1997. It also includes a report to the Congress on the NRC Safety Research Program.

core   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Tax Office prosecututions: Firm and Fair Regulatory Enforcement? [PDF]

In recent years, the Australian Taxation Office has gone to some pains to present itself as a responsive, cooperative, almost friendly, bureaucracy. At the same time, however, the Tax Office has also publicized its ongoing efforts to get tougher on ...
Roche, Declan, Australian National University. Regulatory Institutions Network   +1 more
core  

Pharmaceutical Regulatory Science

International Journal of Pharmaceutical Research and Applications
TitlePharmaceutical Regulatory Science Authors / Editors Editor: Dr. Ravi Shankar Tripathi Co-Editor: Dr. Pravin Badhe Contributing Authors: Sushmita Hiremath; Nikhil Gawas; Bono Naga Sudha; Thokala Ujwala Reddy; Kanchanam AshaDeepthi; Shaik Shabana; Dr. Vivek R. Mallurwar; Reema Sanghvi; Dr.
I.Joseph Immanuel, Dr. S.Mohamedhalith Dr. S.Mohamedhalith, Mrs .A.Meena Mrs .A.Meena, S.Jeeva S.Jeeva, S.Jeevanandham S.Jeevanandham, S.Jegan S.Jegan, K.Kabilan K.Kabilan   +6 more
openaire   +3 more sources

Regional Trends in the Opioid Epidemic Using Safety Signals of Drug Abuse and Dependence: A Disproportionality Analysis Using VigiBase

Drugs - Real World Outcomes
Background The opioid epidemic, once a major concern in the United States, has escalated worldwide through three waves driven by prescription and synthetic opioids like oxycodone and fentanyl. Regional patterns of misuse and dependence remain unclear due
Bohyun Suh, Hyung Suk Oh, Ju-Young Shin, Ju Hwan Kim   +3 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

A regulatory approach for the Australian charities and not-for-profit commission: A discussion paper [PDF]

, 2013
This discussion paper provides the basis for dialogue about a suitable regulatory framework for the not-for-profit sector (NFP).1 The purpose of regulation is to steer the flow of events.
Braithwaite, Valerie, Australian National University. Regulatory Institutions Network   +1 more
core  

Advances and clinical potential of epigenome editing

Cellular and Molecular Life Sciences
Epigenome editing has emerged as a powerful platform to modulate gene expression in a precise and reversible manner. Recent advances have significantly improved the efficiency, specificity, and durability of epigenome editing systems, enabling fine-tuned
Insung Choi, Sueon Kim, Inwha Baek
doaj   +1 more source

Important missing information in Japan's risk management plans: a cross-sectional analysis after a decade of implementation

Frontiers in Medicine
IntroductionMore than 10 years have passed since Japan introduced risk management plans (RMPs), yet research focusing on important missing information (IMI) remains limited.
Natsuko Kameyama, Natsuko Kameyama, Ayana Ide, Hideki Maeda, Hideki Maeda   +4 more
doaj   +1 more source