Results 61 to 70 of about 29,276,589 (300)

Serum Myonectin Levels Are Positively Associated With Physical Function and Lower Frailty‐Related Limitation in Maintenance Hemodialysis Patients: A Cross‐Sectional Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Maintenance hemodialysis (MHD) patients frequently suffer from frailty, characterized by reduced physical function and poor prognosis. Myokines, such as myonectin, secreted by muscle, are emerging regulators of systemic health. This study investigated the relationship between serum myonectin, adipokines (adiponectin, omentin), and ...
Kenichi Kono   +7 more
wiley   +1 more source

Surveillance Approaches for Regulatory Science

open access: yes, 2016
The essential function of a regulatory agency is to enforce laws enacted by the government and regulations established by the agency. For example, the US Food and Drug Administration (FDA) is charged with protecting public health by the regulation of ...
Dai, Susie Y.
core   +1 more source

Exploring staffing and hospital factors associated with WardPharm-1 filing in Japan: a nationwide observational study

open access: yesJournal of Pharmaceutical Health Care and Sciences
Background The healthcare system of Japan faces mounting challenges, including population aging, medical complexity, and workforce shortages. Hospital pharmacists are expected to ensure the safe and effective use of medicines and contribute to ...
Masayuki Kaneda   +3 more
doaj   +1 more source

Trends in oncology drug lags in Japan from 2001 to 2020: A cross‐sectional study

open access: yesClinical and Translational Science, 2023
Anticancer drugs are essential in the treatment of serious diseases, but their applications are limited by drug lags. This study investigated the characteristics of anticancer drugs approved in Japan over the past 20 years and compared the drug lag ...
Hideki Maeda   +5 more
doaj   +1 more source

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa   +7 more
wiley   +1 more source

Global trends in e-labeling: a comprehensive geographical perspective

open access: yesFrontiers in Medicine
IntroductionThis study presents a comprehensive analysis of e-labeling adoption for medicinal products worldwide. Electronic Product Information (ePI) makes available the most up to date approved medicinal product information on an electronic platform ...
Agnès Dangy-Caye   +6 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Nuclear regulatory legislation, 104th Congress, Volume 1, No. 4

open access: yes, 1997
This document is the first of two volumes compiling statutes and material pertaining to nuclear regulatory legislation through the 104th Congress, 2nd Session. It is intended for use as a U.S.

core   +1 more source

Biopesticides, regulatory innovation and the regulatory state [PDF]

open access: yes, 2009
This article analyses regulatory innovation. It considers, in particular, how a regulatory environmental agency has been encouraged to innovate in the area of biopesticides.
Justin Greaves, Greaves, Justin
core   +1 more source

Healthcare resource utilisation and costs in infants with confirmed respiratory syncytial virus infections: a national population cohort study

open access: yesBMC Infectious Diseases
Background Respiratory syncytial virus (RSV) is the leading cause of severe respiratory infections in infants worldwide, significantly affecting their health and contributing to the global healthcare burden.
Hyun Jin Han   +4 more
doaj   +1 more source

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