Results 11 to 20 of about 302,293 (261)
Emerging roles of i-motif in gene expression and disease treatment
Frontiers in Pharmacology, 2023 As non-canonical nucleic acid secondary structures consisting of cytosine-rich nucleic acids, i-motifs can form under certain conditions. Several i-motif sequences have been identified in the human genome and play important roles in biological regulatory
Xiaoqing Luo +8 more
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The Emerging Landscape of Long Non-Coding RNAs in Wilms Tumor
Frontiers in Oncology, 2022 Long noncoding RNAs (LncRNAs) are transcripts of nucleic acid sequences with a length of more than 200 bp, which have only partial coding capabilities.
Qiang Liu
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G-Quadruplex-Binding Proteins: Promising Targets for Drug Design
Biomolecules, 2022 G-quadruplexes (G4s) are non-canonical secondary nucleic acid structures. Sequences with the potential to form G4s are abundant in regulatory regions of the genome including telomeres, promoters and 5′ non-coding regions, indicating they fulfill ...
Huiling Shu +4 more
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Toward Establishing an Ideal Adjuvant for Non-Inflammatory Immune Enhancement
Cells, 2022 The vertebrate immune system functions to eliminate invading foreign nucleic acids and foreign proteins from infectious diseases and malignant tumors.
Tsukasa Seya +2 more
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VirF-independent regulation of Shigella virB transcription is mediated by the small RNA RyhB. [PDF]
PLoS ONE, 2012 Infection of the human host by Shigella species requires the coordinated production of specific Shigella virulence factors, a process mediated largely by the VirF/VirB regulatory cascade.
William H Broach +4 more
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Frontiers in Oncology, 2021 Repetitive DNA sequences (repeats) colonized two-third of human genome and a majority of repeats comprised of transposable genetic elements (TE). Evolutionary distinct categories of TE represent nucleic acid sequences that are repeatedly copied from and ...
Gennadi V. Glinsky, Gennadi V. Glinsky
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Identification of small RNAs abundant in Burkholderia cenocepacia biofilms reveal putative regulators with a potential role in carbon and iron metabolism [PDF]
, 2017 Small RNAs play a regulatory role in many central metabolic processes of bacteria, as well as in developmental processes such as biofilm formation. Small RNAs of Burkholderia cenocepacia, an opportunistic pathogenic beta-proteobacterium, are to date not ...
Coenye, Tom +2 more
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Biotechnology for Biofuels, 2019 Background Soil ascomycete fungi produce plant-biomass-degrading enzymes to facilitate nutrient and energy uptake in response to exogenous stress. This is controlled by a complex signal network, but the regulatory mechanisms are poorly understood.
Lu-Sheng Liao +6 more
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Cross-species regulatory sequence activity prediction.
PLoS Computational Biology, 2020 Machine learning algorithms trained to predict the regulatory activity of nucleic acid sequences have revealed principles of gene regulation and guided genetic variation analysis.
David R Kelley
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Transcriptional Regulation of Carbohydrate Utilization Pathways in the Bifidobacterium Genus
Frontiers in Microbiology, 2016 Bifidobacteria, which represent common commensals of mammalian gut, are believed to have positive effects on human health. The influence of certain non-digestible carbohydrates (and their use as so-called prebiotics) on growth and metabolic activity of ...
Matvei S Khoroshkin +4 more
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