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Members of the Regulatory Lymphocyte Club in Common Variable Immunodeficiency
Frontiers in Immunology, 2022 The role of CD4 T regulatory cells is well established in peripheral tolerance and the pathogenesis of the murine model and human autoimmune diseases.
Sudhir Gupta +2 more
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Predictors of immunosuppressive regulatory T lymphocytes in healthy women. [PDF]
J Cancer Epidemiol, 2012 Immunosuppressive regulatory T (Treg) cells play an important role in antitumor immunity, self-tolerance, transplantation tolerance, and attenuation of allergic response. Higher proportion of Treg cells has been observed in peripheral blood of cancer cases compared to controls.
Hampras SS +6 more
europepmc +4 more sources
Compromised function of regulatory T cells in rheumatoid arthritis and reversal by anti-TNF alpha therapy [PDF]
, 2004 Regulatory T cells have been clearly implicated in the control of disease in murine models of autoimmunity. The paucity of data regarding the role of these lymphocytes in human autoimmune disease has prompted us to examine their function in patients with
Jamie G. Evans +13 more
core +1 more source
Brazilian Oral Research, 2019 : Human Leukocyte Antigen G (HLA-G) is a molecule involved in the tumor immunosuppression and also in the generation of regulatory T (Treg) cells, thus leading to evasion to the immune system host, and consequently, contributing to tumor progression in ...
Amanda Katarinny Goes Gonzaga +4 more
doaj +1 more source
Regulatory T Cell-Enhancing Therapies to Treat Atherosclerosis
Cells, 2021 Experimental studies have provided strong evidence that chronic inflammation triggered by the sub-endothelial accumulation of cholesterol-rich lipoproteins in arteries is essential in the initiation and progression of atherosclerosis.
Hafid Ait-Oufella +2 more
doaj +1 more source
The role of regulatory T cells in the modulation of anti-tumor immune response [PDF]
Srpski Arhiv za Celokupno Lekarstvo, 2013 It has been shown that the loss of regulatory function by deple + Regulatory T cells (Treg) represent a subset of CD4 T cells whose function is to suppress immune responses.
Radosavljević Gordana D. +3 more
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Praxis medica, 2010 <p>Regulatory T cells represent unique CD4+CD25+ population of T lymphocytes, which are involved in many immunological events. These cells have very important role in maintaining peripheral tolerance, prevention of autoimmune diseases, in immunological respond to infection, particularly by intracellular microorganisms as well as in a ...
A. Arsović +4 more
openaire +1 more source
A gene regulatory network armature for T lymphocyte specification [PDF]
Proceedings of the National Academy of Sciences, 2008 Choice of a T lymphoid fate by hematopoietic progenitor cells depends on sustained Notch–Delta signaling combined with tightly regulated activities of multiple transcription factors. To dissect the regulatory network connections that mediate this process, we have used high-resolution analysis of regulatory gene expression ...
Georgescu, Constantin +7 more
openaire +3 more sources
Neurobiology of Disease, 2012 Activated microglia and infiltrating lymphocytes are neuropathological hallmarks of amyotrophic lateral sclerosis (ALS), a fatal motoneuron disease.
Weihua Zhao +4 more
doaj +1 more source
Pathogens, 2023 CD39 is a marker of immune cells such as lymphocytes and monocytes. The CD39/CD73 pathway hydrolyzes ATP into adenosine, which has a potent immunosuppressive effect.
Alaa Elsaghir +5 more
doaj +1 more source