Results 141 to 150 of about 2,996,073 (354)

Regulatory T Cell and T Helper 17 Cell Imbalance in Patients with Unexplained Infertility

International Journal of Women's Health
Liang Lu,1,* Yan Lu,2,* Longyi Zhang2 1Department of Reproductive Center, Affiliated Dongyang Hospital of Wenzhou Medical University, Dongyang, Zhejiang, People’s Republic of China; 2Clinical Laboratory, Affiliated Dongyang Hospital of Wenzhou ...
Lu L, Lu Y, Zhang L
doaj  

Oxidative stress controls regulatory T cell apoptosis and suppressor activity and PD-L1-blockade resistance in tumor

Nature Immunology, 2017
T. Maj, Wei Wang, Joel Crespo, Hongjuan Zhang, Weimin Wang, Shuang Wei, Lili Zhao, Linda Vatan, Irene Shao, Wojciech Szeliga, C. Lyssiotis, J. Liu, Ilona Kryczek, W. Zou   +13 more
semanticscholar   +1 more source

Regulatory T cells and the microenvironment of the malignant B cell of chronic lymphocytic leukemia

, 2019
Georgiana Ene, Ana Maria Vlădăreanu, Horia Bumbea, Ion Dumitru   +3 more
openalex   +1 more source

The Role of Adjuvant 1.25-Dihidroxyvitamin D3 on CD4 + CD25 + CD127 low Regulatory T-cell in Subcutaneous Allergen Specific Immunotherapy [PDF]

, 2018
Melati Sudiro, Teti Madiadipoera, Thaufiq S. Boesoirie, Budi Setiabudiawan   +3 more
openalex   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Neutrophils in patients with chronic coronary syndrome exhibit delayed apoptosis and resistance to regulatory T cell-induced apoptosis – Brief Report [PDF]

Maike Schneider, Camilla Skoglund, Rosanna Chung, L. Jonasson   +3 more
openalex   +1 more source

Type 1 regulatory T cells: a new mechanism of peripheral immune tolerance [PDF]

, 2015
Hanyu Zeng, Rong Zhang, Boquan Jin, Lihua Chen   +3 more
openalex   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source