Results 221 to 230 of about 2,009,353 (358)

Immune regulatory loops determine productive interactions within human T lymphocyte–dendritic cell clusters [PDF]

, 1999
Gernot Stuhler, Anke Zobywalski, Frank Grünebach, Peter Brossart, Volker L. Reichardt, Heidi Barth, Stefan Stevanović, Wolfram Brugger, Lothar Kanz, S F Schlossman   +9 more
openalex   +1 more source

EGFR‐STAT3 activation provides a therapeutic rationale for targeting aggressive ETV1‐positive prostate cancer

Molecular Oncology, EarlyView.
Cotargeting EGFR and STAT3 with Erlotinib and TTI‐101 impairs both 2D and 3D growth of ETV1‐overexpressing prostate cancer cells by disrupting a self‐sustaining ETV1–EGFR positive feedback loop that promotes EGFR and STAT3 expression and phosphorylation (activation).
Elsa Gomes Paiva, Bernardo Orr, Ana Azeredo, Andreia Brandão, Manuel R. Teixeira, Paula Paulo   +5 more
wiley   +1 more source

Genistein enhances anti-PD-1 efficacy in melanoma by suppressing regulatory T cell differentiation and activity. [PDF]

Sci Rep
Mo F, Hong M, Chen X, Wang Q, Dong C.
europepmc   +1 more source

Identification of cis-acting regulatory elements controlling interleukin-4 gene expression in T cells: roles for NF-Y and NF-ATc.

, 1993
Susanne J. Szabo, Jennifer S. Gold, Theresa L. Murphy, Kenneth M. Murphy   +3 more
openalex   +1 more source

Immunologic Self-Tolerance Maintained by Cd25+Cd4+Regulatory T Cells Constitutively Expressing Cytotoxic T Lymphocyte–Associated Antigen 4 [PDF]

, 2000
Takeshi Takahashi, Tomoyuki Tagami, Sayuri Yamazaki, Toshimitsu Uede, Jun Shimizu, Noriko Sakaguchi, Tak W. Mak, Shimon Sakaguchi   +7 more
openalex   +1 more source

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

Molecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon, Moa Stenudd, Margherita Zamboni, Kanar Alkass, Carl‐Johan Eriksson, Lars Pedersen, Alrik Schörling, Anna Thoss, Anders Bergh, Pernilla Wikström, Hans‐Olov Adami, Henrik Toft Sørensen, Henrik Druid, Jonas Frisén   +13 more
wiley   +1 more source

Regulatory T cell therapy in solid organ transplantation: clinical applications and laboratory monitoring strategies. [PDF]

Clin Transplant Res
Nam M.
europepmc   +1 more source

T Regulatory Cells 1 Inhibit a Th2-Specific Response In Vivo [PDF]

, 2000
Françoise Cottrez, Steven D. Hurst, Robert L. Coffman, Hervé Groux   +3 more
openalex   +1 more source

Integrative miRNOMe profiling reveals the miR‐195‐5p–CHEK1 axis and its impact on luminal breast cancer outcomes

Molecular Oncology, EarlyView.
In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková, Marie Ehrlichová, Alžběta Spálenková, Ivona Krus, Simona Šůsová, Viktor Hlaváč, Vlasta Němcová, Renata Koževnikovová, Markéta Trnková, David Vrána, Jiří Gatěk, Kateřina Kopečková, Marcela Mrhalová, Soňa Měšťáková, Pavel Souček   +14 more
wiley   +1 more source

MAIT cells promote cancer progression and regulatory T cell accumulation in bladder tumor microenvironment. [PDF]

J Immunother Cancer
Habaz IA, Ou X, Wang NI, Schincaglia A, Shydlouskaya V, Mahendran A, Martinez-Santiesteban FM, Doolabi D, Bao Y, Movasseghi AR, Haruna J, Power NE, Scholl TJ, Huynh MJ, Sener A, Haeryfar SMM.   +15 more
europepmc   +1 more source