Results 91 to 100 of about 1,141,931 (248)

IL-6-miR-210 Suppresses Regulatory T Cell Function and Promotes Atrial Fibrosis by Targeting Foxp3.

, 2020
YingWei Chen, Guodong Chang, XiaoJie Chen, Yunpeng Li, Haiyu Li, Dong Cheng, Yi Tang, HaiQiang Sang   +7 more
openalex   +2 more sources

Conference Scene: 3Rd Keystone Symposium On T Regulatory Cells [PDF]

, 2009
Alicia N. McMurchy, Megan K. Levings
openalex   +1 more source

Data from Stereotactic Radiotherapy Increases Functionally Suppressive Regulatory T Cells in the Tumor Microenvironment

, 2023
Yuki Muroyama, Thomas R. Nirschl, Christina M. Kochel, Zoila A. Lopez‐Bujanda, Debebe Theodros, Wendy L. Mao, Maria A. Carrera-Haro, Ali Ghasemzadeh, Ariel E. Marciscano, Esteban Velarde, Ada Tam, Christopher J. Thoburn, Muniza Uddin, Alan K. Meeker, Robert A. Anders, Drew M. Pardoll, Charles G. Drake   +16 more
openalex   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Data from Myeloid-Derived Suppressor Cells Promote Cross-Tolerance in B-Cell Lymphoma by Expanding Regulatory T Cells

, 2023
Paolo Serafini, Stephanie Mgebroff, Kimberly Noonan, Ivan Borrello   +3 more
openalex   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

FEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom, Jaewoong Jang, Jung Sun Park, Yong‐Kook Kang   +3 more
wiley   +1 more source

A multiply redundant genetic switch 'locks in' the transcriptional signature of regulatory T cells

, 2012
Wenxian Fu, Ayla Ergün, Ting Lu, Jonathan A. Hill, Sokol Haxhinasto, Marlys S. Fassett, Roi Gazit, Stanley Adoro, Laurie H. Glimcher, Susan Chan, Philippe Kastner, Derrick J. Rossi, James J. Collins, Diane Mathis, Christophe Benoıst   +14 more
openalex   +2 more sources

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Editorial: Immunometabolism of T cells in skin infection, autoimmunity and cancer biology

Frontiers in Immunology, 2023
Lu Peng, Ling Chen, Laura A. Solt, Venina Marcela Dominical, Zhu Shen   +4 more
doaj   +1 more source