Results 31 to 40 of about 1,139,425 (157)

REGULATORY T–CELLS: ORIGIN AND FUNCTION

open access: yesМедицинская иммунология, 2014
. Over the past decade a population of so–called “regulatory T cells” (Treg cells) has been linked to the prevention of autoimmunity. In this review we discuss the molecular mechanisms of Treg cells development and function including the identification ...
I. S. Freidlin
doaj   +1 more source

Regulatory T Cells Restrain Pathogenic T Helper Cells during Skin Inflammation

open access: yesCell Reports, 2018
Summary: Psoriasis is a chronic relapsing, remitting interleukin (IL)-23/IL-17-driven skin disease mediated by the interplay of T cells and polymorphonuclear granulocytes. Although preclinical studies have provided insights into the mechanisms of disease
Tom Hartwig   +10 more
doaj   +1 more source

Persistent immune activation in CVID and the role of IVIg in its suppression

open access: yesFrontiers in Immunology, 2014
Common variable immunodeficiency (CVID) is one of the most common and clinically important primary immune deficiencies. CVID patients have poor humoral immunity resulting in recurrent infections of the gastrointestinal and upper respiratory tracts, as ...
Dominic ePaquin-Proulx   +1 more
doaj   +1 more source

Cholera-Like Enterotoxins and Regulatory T cells

open access: yesToxins, 2010
Cholera toxin (CT) and the heat-labile enterotoxin of E. coli (LT), as well as their non toxic mutants, are potent mucosal adjuvants of immunization eliciting mucosal and systemic responses against unrelated co-administered antigens in experimental ...
Evelyne Kohli   +5 more
doaj   +1 more source

T follicular helper cells and T follicular regulatory cells in autoimmune diseases

open access: yesFrontiers in Immunology, 2023
T follicular helper (Tfh) cells are heterogeneous and mainly characterized by expressing surface markers CXCR5, ICOS, and PD-1; cytokine IL-21; and transcription factor Bcl6.
Jingjing Qi   +4 more
doaj   +1 more source

Regulatory T cells in radiotherapeutic responses

open access: yesFrontiers in Oncology, 2012
Radiation therapy (RT) can extend its influence in cancer therapy beyond what can be attributed to in-field cytotoxicity by modulating the immune system.
Dörthe eSchaue   +3 more
doaj   +1 more source

More Than Effects in Skin: Ultraviolet Radiation-Induced Changes in Immune Cells in Human Blood

open access: yesFrontiers in Immunology, 2021
Cells of the skin and circulation are in constant two-way communication. Following exposure of humans to sunlight or to phototherapy, there are alterations in the number, phenotype and function of circulating blood cells.
Prue H. Hart, Mary Norval
doaj   +1 more source

Follicular lymphoma regulatory T-cell origin and function

open access: yesFrontiers in Immunology
IntroductionFollicular Lymphoma (FL) results from the malignant transformation of germinal center (GC) B cells. FL B cells display recurrent and diverse genetic alterations, some of them favoring their direct interaction with their cell microenvironment,
Stéphane Rodriguez   +16 more
doaj   +1 more source

Regulatory T Cells in Systemic Sclerosis

open access: yesFrontiers in Immunology, 2018
In recent years, accumulating evidence suggest that regulatory T cells (Tregs) are of paramount importance for the maintenance of immunological self-tolerance and immune homeostasis, even though they represent only about 5–10% of the peripheral CD4+ T ...
Camelia Frantz   +3 more
doaj   +1 more source

The Effect of Statins on the Functionality of CD4+CD25+FOXP3+ Regulatory T-cells in Acute Coronary Syndrome: A Systematic Review and Meta-analysis of Randomised Controlled Trials in Asian Populations

open access: yesEuropean Cardiology Review, 2019
Acute coronary syndrome (ACS) is characterised by increased effector cells and decreased regulatory T-cells (Tregs). Statins have been shown to be clinically beneficial in ACS patients.
Nilofer Sorathia   +2 more
doaj   +1 more source

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