Results 121 to 130 of about 279,628 (297)

Abatacept (cytotoxic T lymphocyte antigen 4-immunoglobulin) improves B cell function and regulatory T cell inhibitory capacity in rheumatoid arthritis patients non-responding to anti-tumour necrosis factor-α agents [PDF]

, 2014
Andrea Picchianti Diamanti, Maria Manuela Rosado, Marco Scarsella, Valentina Germano, Ezio Giorda, Simona Cascioli, Bruno Laganà, Raffaele D’Amelio, Rita Carsetti   +8 more
openalex   +1 more source

Bioengineered Pancreatic Cancer Immunosuppressive Microenvironment Models for Screening Immunotherapies

Advanced Healthcare Materials, EarlyView.
Bioengineering tumor‐stroma pancreatic cancer models with potential to emulate the native immunosuppressive tumor microenvironment. Cancer‐on‐a‐bead models exhibited higher relevance for screening immunotherapies and modulating the protumoral PDAC microenvironment. ABSTRACT Pancreatic cancer is notably resistant to treatment, primarily due to its dense
Maria V. Monteiro, Margarida Henriques‐Pereira, Bruno M. Neves, Vítor M. Gaspar, João F. Mano   +4 more
wiley   +1 more source

A Sacrificial 3D Printed Vessel‐on‐Chip Demonstrates a Versatile Approach to Model Granulation Tissue

Advanced Healthcare Materials, EarlyView.
A novel method that combines 3D printing and organ‐on‐chip technology enables the creation of hollow channels lined with endothelial cells through a fibroblast‐populated connective tissue matrix. The model supports stable metabolic culture conditions, angiogenic sprouting, and immune cell migration, thereby demonstrating an easy and versatile method to
Jonas Jäger, Phil Berger, Andrew I. Morrison, Hendrik Erfurth, Maria Thon, Eva‐Maria Dehne, Susan Gibbs, Jasper J. Koning   +7 more
wiley   +1 more source

Genetic and regulatory contributions of the major histocompatibility complex to the developing cytolytic T lymphocyte repertoire. [PDF]

, 1982
Linda A. Sherman
openalex   +1 more source

A Human‐Based Skin‐Lymphoreticular Model‐on‐Chip to Emulate Inflammatory Skin Conditions

Advanced Healthcare Materials, EarlyView.
A human‐based lymphoreticular (LR) model was developed through guided self‐assembly and integrated in a skin‐lymphoreticular co‐culture in a microfluidic organ‐on‐chip to mimic interactions between skin and its draining lymph nodes. The human‐based skin‐lymphoreticular model resembles a minimally functional unit that allows to study interactions ...
Zheng Tan, Partho Protim Adhikary, Dana Wörz, Sarah Hedtrich   +3 more
wiley   +1 more source

Characterization of a novel T lymphocyte protein which binds to a site related to steroid/thyroid hormone receptor response elements in the negative regulatory sequence of the human immunodeficiency virus long terminal repeat

, 1992
Kim Orchard, Georgina Lang, Mary Collins, D.S. Latchman   +3 more
openalex   +2 more sources

Role of the cells of the system of mononuclear phagocytes and regulatory T-lymphocytes in the formation of the state of immunosuppression in sepsis

, 2022
Leonid Titov, M. O. Trusevich, Yu. L. Gorbich   +2 more
openalex   +2 more sources

Microphysiological Systems of Lymphatics and Immune Organs

Advanced Healthcare Materials, EarlyView.
This review surveys recent progress in engineering lymphatic microenvironments and immune organoids within microphysiological systems, emphasizing innovative strategies to recreate the biochemical and biophysical complexity of native lymphatic tissues.
Ishita Jain, Ankur Singh, Andrés J. García   +2 more
wiley   +1 more source

Specific features of lymphoid infiltration in liver biopsy in patients with chronic viral hepatitis B and C

Терапевтический архив, 2011
Aim. To study characteristics of leukocytic infiltration of the liver in patients with chronic viral hepatitis B and C (CVHB and CVHC) with consideration of hepatitis activity and fibrosis severity. Material and methods.
Karina Turakbaevna Umbetova, Anna Svyatoslavovna Lazareva, Mikhail Valentinovich Kiselevskiy, Yuriy Georgievich Parkhomenko, Elena Vasil'evna Volchkova, Sergey Grigor'evich Pak, K T Umbetova, A S Lazareva, M V Kiselevsky, Yu G Parkhomenko, E V Volchkova, S G Pak   +11 more
doaj  

BACH2: The Future of Induced T-Regulatory Cell Therapies

Cells
BACH2 (BTB Domain and CNC Homolog 2) is a transcription factor that serves as a central regulator of immune cell differentiation and function, particularly in T and B lymphocytes.
Daniel Zwick, Mai Tram Vo, Young Jun Shim, Helena Reijonen, Jeong-su Do   +4 more
doaj   +1 more source