Results 171 to 180 of about 1,033,187 (394)

Cytokine control of parasite-specific anergy in human lymphatic filariasis. Preferential induction of a regulatory T helper type 2 lymphocyte subset. [PDF]

, 1993
Christopher L. King, Siddhartha Mahanty, V. Kumaraswami, J S Abrams, J. Regunathan, Kunthala Jayaraman, Eric A. Ottesen, Thomas B. Nutman   +7 more
openalex   +1 more source

Immunocto: a massive immune cell database auto-generated for histopathology [PDF]

arXiv
With the advent of novel cancer treatment options such as immunotherapy, studying the tumour immune micro-environment (TIME) is crucial to inform on prognosis and understand potential response to therapeutic agents. A key approach to characterising the TIME may be through combining (1) digitised microscopic high-resolution optical images of hematoxylin
arxiv  

Biologically‐Inspired Melt Electrowriting for the Generation of Highly Biomimetic Functional Myocardium

Advanced Functional Materials, EarlyView.
In this work, melt electrowriting is used to fabricate a 3D printed scaffold design that generates engineered cardiac tissues with in‐plane contraction, mimicking natural myocardium. It is shown that these tissues display advanced maturation and functionality.
Olalla Iglesias‐García, María Flandes‐Iparraguirre, Pilar Montero‐Calle, Ricardo M. Rosales, Asier Ullate‐Agote, Andrea Sánchez‐Bueno, Eduardo Larequi, Ilazki Anaut‐Lusar, Nicolás Laita, Aida Oliván‐Viguera, Elena Iglesias, Gloria Abizanda, Patxi San Martín‐Úriz, Paula Aguirre‐Ruiz, Xabier L. Aranguren, Manuel García de Yébenes, Juan José Gavira, Miguel Ángel Martínez, Estefanía Peña, Manuel Doblaré, Elena M. de‐Juan‐Pardo, Esther Pueyo, Felipe Prosper, Manuel M. Mazo Vega   +23 more
wiley   +1 more source

IL-2 and IL-15 drive intrathymic development of distinct periphery-seeding CD4⁺Foxp3⁺ regulatory T lymphocytes. [PDF]

Front Immunol, 2022
Apert C, Galindo-Albarrán AO, Castan S, Detraves C, Michaud H, McJannett N, Haegeman B, Fillatreau S, Malissen B, Holländer G, Žuklys S, Santamaria JC, Joffre OP, Romagnoli P, van Meerwijk JPM.   +14 more
europepmc   +1 more source

Characterization of a novel T lymphocyte protein which binds to a site related to steroid/thyroid hormone receptor response elements in the negative regulatory sequence of the human immunodeficiency virus long terminal repeat [PDF]

, 1992
Kim Orchard, Georgina Lang, Mary Collins, D.S. Latchman   +3 more
openalex   +1 more source

Optimizing Angiopep‐2 Density on Polymeric Nanoparticles for Enhanced Blood–Brain Barrier Penetration and Glioblastoma Targeting: Insights From In Vitro and In Vivo Experiments

Advanced Functional Materials, EarlyView.
The Angiopep‐2 peptide density on polymeric nanoparticles significantly impacts blood–brain barrier (BBB) penetration. This study explores this nuanced relationship using various in vitro models and in vivo assays, revealing that dynamic models better predict BBB penetration.
Weisen Zhang, Ahmed Refaat, Haoqin Li, Douer Zhu, Ziqiu Tong, Joseph Anthony Nicolazzo, Bo Peng, Hua Bai, Lars Esser, Nicolas Hans Voelcker   +9 more
wiley   +1 more source

Regulační CD8+ T lymfocyty [PDF]

, 2017
Regulatory T cells are essential for the maintenance of peripheral immune tolerance, preventing alloimmunity and pathogen-induced immunopathology. While regulatory CD4+ T lymphocytes have been studied for over two decades, the existence of regulatory T ...
Chadimová, Tereza
core  

Destruction of CD4 T Lymphocytes Alone Cannot Account for their Long-term Decrease in AIDS [PDF]

arXiv, 2000
Following previous models describing a quasi steady state (QSS) for the evolution of HIV infection and AIDS, we have developed a larger formalism simulating the long-term evolution of the QSS We show that the long-term evolution of AIDS cannot be explained by the destruction alone of CD4 T cells, either directly or indirectly.
arxiv  

Strategies to Design and Optimize Artificial Antigen‐Presenting Cells for T Cell Expansion in Cancer Immunotherapy

Advanced Functional Materials, EarlyView.
This review highlights recent advances in engineering artificial antigen‐presenting cells (aAPCs) as alternatives to dendritic cells for T cell expansion. Key design principles inspired by the immunological synapse are discussed, with emphasis on strategies for polyclonal and antigen‐specific T cell expansion.
Nguyen Thi Nguyen, Yu Seok Youn
wiley   +1 more source

Ex vivo expansion of dysfunctional regulatory T lymphocytes restores suppressive function in Parkinson's disease. [PDF]

NPJ Parkinsons Dis, 2021
Thome AD, Atassi F, Wang J, Faridar A, Zhao W, Thonhoff JR, Beers DR, Lai EC, Appel SH.   +8 more
europepmc   +1 more source