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REGULATORY T-LYMPHOCYTES IN LYMPHOMAGENESIS

2020
B-cell lymphomas are a heterogenous group of tumours that account for 85% of all non-Hodgkin lymphomas (NHL), tumours derived from cells of lymphoid lineage. B-lymphomas originate from various developmental stages of B lymphocytes. Classical Hodgkin’s lymphoma (cHL) also originates from B lymphocytes.
Gršković, Paula   +5 more
openaire  

Regulatory T cells in chronic lymphocytic leukemia

Comparative Clinical Pathology, 2014
Controversial results concerning the prognostic value of the regulatory T (Treg) cell percentage in peripheral blood of chronic lymphocytic leukemia (CLL) patients have been reported in the previous studies. This study aimed to estimate the prognostic relevance of Treg cells in untreated CLL patients at diagnosis.
Tawfik Elkhodary   +5 more
openaire   +1 more source

Contingent Genetic Regulatory Events in T Lymphocyte Activation

Science, 1989
Interaction of antigen in the proper histocompatibility context with the T lymphocyte antigen receptor leads to an orderly series of events resulting in morphologic change, proliferation, and the acquisition of immunologic function. In most T lymphocytes two signals are required to initiate this process, one supplied by the antigen receptor and the ...
openaire   +2 more sources

Lag3+ regulatory T lymphocytes in critical carotid artery stenosis

Clinical and Experimental Medicine, 2019
The aim of this study was to evaluate CD25+ and Lag3+ T regulatory subpopulations in patients with critical carotid artery stenosis (CAS) and Stanford-A acute aortic dissection (AAD). CD25+ and Lag3+ were measured in 36 patients affected by CAS and 24 patients with Stanford type A AAD.
Del Porto F.   +7 more
openaire   +3 more sources

[Regulatory T lymphocytes CD4(+): current issues].

Medecine sciences : M/S, 2012
Regulatory T cells (Treg) are involved in the maintenance of peripheral tolerance and in the prevention of autoimmune diseases. They are also essential to the regulation of immune responses observed in allergy, transplantation, cancers and infectious diseases. Most of Treg, called natural, differentiate in the thymus and are defined by their expression
Aurélie, Siri   +2 more
openaire   +1 more source

Regulatory factors for initial T lymphocyte lineage specification

Current Opinion in Hematology, 2007
Initiation of T lymphocyte development depends on balanced regulatory inputs from multiple essential transcription factors. This review highlights contributions of E2A, hematopoietic transcription factor PU.1, growth factor independence (Gfi)-1, T cell factor (TCF)-1, and Runx factors and their interactions with the Notch pathway to promote T cell ...
openaire   +3 more sources

Regulatory Interactions between Virgin and Memory CD4 T Lymphocytes

Cellular Immunology, 1996
Naive and memory CD4 T cells from mouse spleen, alone or in a 1:1 mixture, were tested for Con A-induced proliferation in limiting dilution cultures. Dose-response curves for naive cells were linear, but curves for memory cells were hyperbolic, suggesting that positive responses required the activation of several cells of the memory type. Mixtures (1:1)
I M, Dozmorov, R A, Miller
openaire   +2 more sources

Regulatory Lymphocytes in T Cell Functions in Chickens

1977
Our contemporary understanding of the immune system involves the concept of two distinct expressions of immunity as well as the division of lymphocyte types into functional subpopulations. Inherent in the development of this complexity is the discernment that some form of control mechanism must have evolved simultaneously.
openaire   +2 more sources

RELATIONSHIP BETWEEN MICROVASCULAR T REGULATORY LYMPHOCYTES AND CIRCULATING LYMPHOCYTES

2015
Objective: Both innate and adaptive immune systems may contribute to the pathogenesis of cardiovascular disease and vascular remodeling through inflammation and oxidative stress. Particularly, the balance between Th1 effector lymphocytes (producing interferon-[gamma]), Th 17 (producing IL-17) and T regulatory (Treg) lymphocytes, which elicit an anti ...
DE CIUCEIS, Carolina   +18 more
openaire   +1 more source

The role of regulatory t lymphocytes in asthma pathogenesis

Current Allergy and Asthma Reports, 2005
Several subtypes of regulatory or suppressive T cells have been described that can prevent activation of effector T cells in vitro and in vivo in animal models. Recent evidence suggests a deficit in suppressive activity of both CD4(+)CD25(+) regulatory T cells, and interleukin (IL)-10 producing regulatory T cells may play a role in development of ...
openaire   +2 more sources

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