Results 71 to 80 of about 1,662,190 (297)

Shear strength analysis of concrete beams reinforced with GFRP bars using strut and tie model [PDF]

open access: yes, 2011
This dissertation presents an experimental investigation on the behavior and ultimate shear strength of reinforced concrete beam. Sixteen reinforced concrete beams was design and tested to failure. This study consists of two series of beams, which are
Mokhtar, Norfaniza
core  

Fine-grained acceleration control for autonomous intersection management using deep reinforcement learning

open access: yes, 2017
Recent advances in combining deep learning and Reinforcement Learning have shown a promising path for designing new control agents that can learn optimal policies for challenging control tasks.
Givargis, Tony, Mirzaei, Hamid
core   +1 more source

The role and implications of mammalian cellular circadian entrainment

open access: yesFEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Computer Vision-Based Structural Displacement Monitoring and Modal Identification with Subpixel Localization Refinement

open access: yesAdvances in Civil Engineering, 2022
In conventional structural health monitoring (SHM), the installation of sensors and data acquisition devices will affect the regular operation of structures to a certain extent and is also expensive.
Tao Liu, Yu Lei, Yibing Mao
doaj   +1 more source

Distributional Reinforcement Learning with Quantile Regression

open access: yes, 2017
In reinforcement learning an agent interacts with the environment by taking actions and observing the next state and reward. When sampled probabilistically, these state transitions, rewards, and actions can all induce randomness in the observed long-term
Bellemare, Marc G.   +3 more
core   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

External Prestressing Bridge Reinforcement Technology Review

open access: yesMATEC Web of Conferences, 2015
Externally prestressed bridge can not only limit and reduce the cracks and deformation of the structure, improve the rigidity and bearing capacity of structure, improve the stress state of structure, but also have less interference for bridge operation ...
Zhu Hanbing, Yang Yaxun, Fan Weiya
doaj   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

open access: yesMolecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez   +17 more
wiley   +1 more source

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias   +12 more
wiley   +1 more source

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