Results 11 to 20 of about 160,770 (374)

Cellular rejuvenation: molecular mechanisms and potential therapeutic interventions for diseases

open access: yesSignal Transduction and Targeted Therapy, 2023
The ageing process is a systemic decline from cellular dysfunction to organ degeneration, with more predisposition to deteriorated disorders. Rejuvenation refers to giving aged cells or organisms more youthful characteristics through various techniques ...
Shuaifei Ji   +9 more
doaj   +2 more sources

Senescence in Mesenchymal Stem Cells: Functional Alterations, Molecular Mechanisms, and Rejuvenation Strategies

open access: yesFrontiers in Cell and Developmental Biology, 2020
Mesenchymal stem cells (MSCs) are multipotent cells capable of self-renewal and differentiation. There is increasing evidence of the therapeutic value of MSCs in various clinical situations, however, these cells gradually lose their regenerative ...
Jing Liu   +6 more
doaj   +2 more sources

Carbon Deposit Analysis in Catalyst Deactivation, Regeneration, and Rejuvenation.

open access: yesAngewandte Chemie, 2023
Hydrocarbon conversion catalysts suffer from deactivation by deposition or formation of carbon deposits. Carbondeposit formation is thermodynamically favored above 350 °C, even in hydrogen-rich environments.
E. Vogt, Donglong Fu, B. Weckhuysen
semanticscholar   +1 more source

Umbilical cord‐derived mesenchymal stem cell secretome promotes skin regeneration and rejuvenation: From mechanism to therapeutics

open access: yesCell Proliferation, 2023
How to effectively repair cutaneous wounds and promote skin rejuvenation has always been a challenging issue for clinical medicine and medical aesthetics.
Xixian Li   +4 more
semanticscholar   +1 more source

Cell-type-specific aging clocks to quantify aging and rejuvenation in neurogenic regions of the brain

open access: yesNature Aging, 2022
The diversity of cell types is a challenge for quantifying aging and its reversal. Here we develop ‘aging clocks’ based on single-cell transcriptomics to characterize cell-type-specific aging and rejuvenation. We generated single-cell transcriptomes from
Matthew T. Buckley   +11 more
semanticscholar   +1 more source

Unraveling the threshold stress of structural rejuvenation of metallic glasses via thermo-mechanical creep

open access: greenScience China Physics Mechanics and Astronomy, 2022
Gan Ding   +4 more
openalex   +3 more sources

Ageing as a software design flaw

open access: yesGenome Biology, 2023
Ageing is inherent to all human beings, yet why we age remains a hotly contested topic. Most mechanistic explanations of ageing posit that ageing is caused by the accumulation of one or more forms of molecular damage.
João Pedro de Magalhães
doaj   +1 more source

Epigenetic rejuvenation by partial reprogramming

open access: yesBioessays, 2023
Rejuvenation of cells by reprogramming toward the pluripotent state raises increasing attention. In fact, generation of induced pluripotent stem cells (iPSCs) completely reverses age‐associated molecular features, including elongation of telomeres ...
Deepika Puri, W. Wagner
semanticscholar   +1 more source

Applications of Mesenchymal Stem Cells in Skin Regeneration and Rejuvenation

open access: yesInternational Journal of Molecular Sciences, 2021
Mesenchymal stem cells (MSCs) are multipotent stem cells derived from adult stem cells. Primary MSCs can be obtained from diverse sources, including bone marrow, adipose tissue, and umbilical cord blood. Recently, MSCs have been recognized as therapeutic
Hantae Jo   +5 more
semanticscholar   +1 more source

Combined Effects of Annealing and Cyclic Loading on Structural Rejuvenation and Mechanical Properties of CuZr Metallic Glass: A Molecular Dynamics Study

open access: yesMaterials Research, 2022
Structural rejuvenation is one of the key topics in the field of metallic glasses (MGs). In this work, we evaluated the combined effects of annealing treatment and elastic cyclic loading to discover pathways for promoting structural rejuvenation and ...
Agus Dwi Anggono   +7 more
doaj   +1 more source

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