Results 61 to 70 of about 103,312 (279)
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Atomistic modeling of heat treatment processes for tuning the mechanical properties of disordered solids [PDF]
, 2019 We investigate the effect of a single heat treatment cycle on the potential energy states and mechanical properties of metallic glasses using molecular dynamics simulations.
Priezjev, Nikolai V.
core +3 more sources
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Age Progression and Regression with Spatial Attention Modules
, 2019 Age progression and regression refers to aesthetically render-ing a given face image to present effects of face aging and rejuvenation, respectively. Although numerous studies have been conducted in this topic, there are two major problems: 1) multiple ...
Li, Qi, Liu, Yunfan, Sun, Zhenan
core +1 more source
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
Rheological aging and rejuvenation in solid friction contacts
, 2002 We study the low-velocity (0.1--100 $\mu$m.s$^{-1}$) frictional properties of interfaces between a rough glassy polymers and smooth silanized glass, a configuration which gives direct access to the rheology of the adhesive joints in which shear localizes.
Baumberger, T., Bureau, L., Caroli, C.
core +1 more source
Numerical Study on Aging Dynamics in the 3D Ising Spin-Glass Model. III. Cumulative Memory and `Chaos' Effects in the Temperature-Shift Protocol [PDF]
, 2002 The temperature ($T$)-shift protcol of aging in the 3 dimensional (3D) Edwards- Anderson (EA) spin-glass (SG) model is studied through the out-of-phase component of the ac susceptibility simulated by the Monte Carlo method.
Hukushima, Koji, Takayama, Hajime
core +1 more source
MATEC Web of Conferences, 2018 While software rejuvenation is used to prevent severe software failures, existing researches generally choose the constant-value periodic policy through steady-state reliability optimization.
He Pan, Liu Gang, Yuan Yue
doaj +1 more source
AGE BITUMEN REJUVENATION INCORPORATING REJUVENATORS
Jurnal Tekno, 2022 To restore the performance of old bitumen which has been stiff and hard to become maltenes, it is necessary to add a rejuvenator to makes the old bitumen will soften and the performance of the bitumen will increase. This paper presents the results of physical property tests of aged bitumen incorporating rejuvenators.
openaire +1 more source