Results 61 to 70 of about 113,150 (329)
Knowing how proteases recognise preferred substrates facilitates matching proteases to applications. The S1′ pocket of protease EA1 directs cleavage to the N‐terminal side of hydrophobic residues, particularly leucine. The S1′ pocket of thermolysin differs from EA's at only one position (leucine in place of phenylalanine), which decreases cleavage ...
Grant R. Broomfield +3 more
wiley +1 more source
Rejuvenation of ‘Make in India’
Initially, Covid-19 outbreak drew the progressive economy towards regression, but later with India being seen as a prime investment destination over China exacerbating the current scenario, there is a comeback of the failed campaign ‘Make In India’ to light, with global pharmaceuticals companies eyeing on India.
Caleb, Mervin Felix, AC, Kiran Kumar
openaire +1 more source
C‐mannosylation is a unique form of protein glycosylation. In this study, we demonstrated that ADAMTS1 is C‐mannosylated at Trp562 and Trp565 in human testicular germ cell tumor NEC8 cells. We found that C‐mannosylation of ADAMTS1 is essential for its secretion, processing, enzymatic activity, and ability to promote vasculogenic mimicry. These findings
Takato Kobayashi +5 more
wiley +1 more source
In Vivo Skin Regeneration and Wound Healing Using Cell Micro-Transplantation
Background: The accumulation of senescent cells in tissues alters tissue homeostasis and affects wound healing. It is also considered to be the main contributing factor to aging.
Lucia Nanić +6 more
doaj +1 more source
Atomistic modeling of heat treatment processes for tuning the mechanical properties of disordered solids [PDF]
We investigate the effect of a single heat treatment cycle on the potential energy states and mechanical properties of metallic glasses using molecular dynamics simulations.
Priezjev, Nikolai V.
core +3 more sources
The Arabidopsis mutants hls1 hlh1 and amp1 lamp1 exhibit pleiotropic developmental phenotypes. Although the functions of the causative genes remain unclear, they act in the same genetic pathway and are thought to generate non‐cell‐autonomous signals.
Takashi Nobusawa, Makoto Kusaba
wiley +1 more source
Chronic Helicobacter pylori infection causes gastric cancer via the progression of precancerous chronic atrophic gastritis (CAG). Therefore, repairing gastric atrophy could be a useful strategy in preventing H.
Jong Min Park +3 more
doaj +1 more source
Numerical Study on Aging Dynamics in the 3D Ising Spin-Glass Model. III. Cumulative Memory and `Chaos' Effects in the Temperature-Shift Protocol [PDF]
The temperature ($T$)-shift protcol of aging in the 3 dimensional (3D) Edwards- Anderson (EA) spin-glass (SG) model is studied through the out-of-phase component of the ac susceptibility simulated by the Monte Carlo method.
Hukushima, Koji, Takayama, Hajime
core +1 more source
Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes
Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley +1 more source
Rheological aging and rejuvenation in solid friction contacts
We study the low-velocity (0.1--100 $\mu$m.s$^{-1}$) frictional properties of interfaces between a rough glassy polymers and smooth silanized glass, a configuration which gives direct access to the rheology of the adhesive joints in which shear localizes.
Baumberger, T., Bureau, L., Caroli, C.
core +1 more source

