Results 101 to 110 of about 24,582,015 (196)
RELAXIN-3/RXFP3 systems and central stress- and anxiety-related circuits in mice
, 2015 RELAXIN-3/RXFP3 systems and central stress- and anxiety-related circuits in ...
E Timofeeva (13357596) +6 more
core
Effect of relaxin on heart rate and relaxin serum concentration.
, 2016 (A) Rat relaxin was increased during pregnancy in transgenic and non-transgenic control rats. (B) Telemetrically measured heart rates. Relaxin treatment leads to an immediately increase in heart rate compared to vehicle treated rats.
Florian Herse (252632) +7 more
core +1 more source
Structural insights into G protein-coupled receptor signaling [PDF]
Structural DynamicsG protein-coupled receptors (GPCRs) are the largest single family of transmembrane proteins encoded in the human genome, and they are among the most successful classes of therapeutic drug targets of all time.
Andrew Kruse
doaj +1 more source
, 2014 Animal and clinical studies of gene-environment interactions have helped elucidate the mechanisms involved in the pathophysiology of several mental illnesses including anxiety, depression, and schizophrenia; and have led to the discovery of improved ...
AW Walker (14876659) +6 more
core
Relaxin and gastrointestinal motility [PDF]
, 2013 Relaxin is involved in a variety of functions. Among them, relaxin influences gastrointestinal motility in mice mainly regulating the biosynthesis of nitric oxide, considered as the main substance causing smooth muscle relaxations.
Baccari, Maria Caterina +3 more
core +1 more source
Relaxin-2 drives regenerative healing and suppresses scar formation
Abstract Fibrotic scarring is a pervasive and unresolved challenge in medicine, leading to permanent disfigurement, impaired mobility, and severe disruption of basic skin functions including elasticity, barrier protection, and thermoregulation.
Amanda K. Williamson +6 more
openaire +2 more sources
Relaxin-3 receptor (Rxfp3) gene deletion reduces operant sucrose- but not alcohol-responding in mice
, 2015 The pervasive use of refined sugars in highly accessible, palatable foods and persistent exposure to reinforcing food-associated cues has contributed to overconsumption of sugar-rich diets and the current obesity epidemic in Western society.
AW Walker (14876659) +3 more
core
Relaxin-3 receptor (RXFP3) signalling mediates stress-related alcohol preference in mice
, 2015 Stressful life events are causally linked with alcohol use disorders (AUDs), providing support for a hypothesis that alcohol consumption is aimed at stress reduction. We have previously shown that expression of relaxin-3 mRNA in rat brain correlates with
AW Walker (14876659) +6 more
core
, 2009 Endometriosis is an important contributing factor to chronic pelvic pain and infertility. Matrix metalloproteinases (MMPs) and vascular endothelial growth factor (VEGF) have each been implicated in the establishment of endometriotic lesions.
MORELLI, S. S. +5 more
core +1 more source
Prognostic significance of relaxin-2 and S100A4 expression in osteosarcoma.
European review for medical and pharmacological sciences, 2015 Relaxin-2 (RLN2) and calcium-binding protein S100A4 was overexpressed in many cancers. Experimental evidence indicated enhanced tumor cell invasion by RLN2 involves the upregulation of S100A4. However, the relationship between them in cancers is not clear.
H, Huang, H-Y, Zheng, Z-L, Liu, L, Zhang
openaire +1 more source