The Evolving Landscape of Pulmonary Hypertension Treatment: From Vasodilation to Disease Modification. [PDF]
Ayalasomayajula S +8 more
europepmc +1 more source
Polystyrene nanoplastics and benzo(a)pyrene synergistically induce lung fibrosis and inflammation via relaxin signalling in mice. [PDF]
Chen Y +8 more
europepmc +1 more source
Analysis of DNA methylation markers for diagnosing cervical precancer and cancer: A single-center cross-sectional study. [PDF]
Chen X +8 more
europepmc +1 more source
Exploring the Cyclic Patterns of Secondary Hair Follicles in Cashmere Goats Based on Skin Transcriptome Data. [PDF]
Gong G +7 more
europepmc +1 more source
Biomarkers of Injury Severity in Shoulder Instability and Posttraumatic Osteoarthritis. [PDF]
Rooney PW +9 more
europepmc +1 more source
Relaxin-3 systems in the brain—The first 10 years
The relaxin-3 gene was identified in 2001 by searching the human genome database for homologues of the relaxin hormone, and was subsequently discovered to encode a highly conserved neuropeptide in mammals and lower species.
Craig M. Smith +2 more
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The dual and multifaceted role of relaxin-2 in cancer
Clinical and Translational Oncology, 2023The continuous increase in cancer-associated deaths despite the substantial improvement in diagnosis and treatment has sparked discussions on the need for novel biomarkers and therapeutic strategies for cancer. Although increasing evidence has demonstrated the pivotal role of relaxin-2 in multiple cancers, their role is a double-edged sword with both ...
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An optimized chemical synthesis of human relaxin‐2
Journal of Peptide Science, 2010AbstractHuman gene 2 relaxin (RLX) is a member of the insulin superfamily and is a multi‐functional factor playing a vital role in pregnancy, aging, fibrosis, cardioprotection, vasodilation, inflammation, and angiogenesis. RLX is currently applied in clinical trials to cure among others acute heart failure, fibrosis, and preeclampsia.
Kostas K, Barlos +3 more
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Signalling profiles of H3 relaxin, H2 relaxin and R3(BΔ23–27)R/I5 acting at the relaxin family peptide receptor 3 (RXFP3) [PDF]
The fulltext of this publication will be made publicly available after relevant embargo periods have lapsed and associated copyright clearances obtained.BACKGROUND AND PURPOSE: Relaxin family peptide receptor 3 (RXFP3) is expressed in brain areas ...
John D Wade, Roger J. Summers
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