Results 171 to 180 of about 24,582,015 (196)
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Signal Switching after Stimulation of LGR7 Receptors by Human Relaxin 2
Annals of the New York Academy of Sciences, 2005Abstract: Previous studies have described a biphasic cAMP response after stimulation of LGR7 by human gene 2 (H2) relaxin, involving both adenylate cyclase and PI3‐kinase activity. The current study identifies the upstream involvement of Gi in the PI3‐kinase‐mediated response, likely the result of receptor signal switching.
Michelle L, Halls +2 more
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Pirfenidone & relaxin: 2 new hopes for fibrotic disease
Inpharma Weekly, 1997Pirfenidone and relaxin are both under investigation for the treatment of fibrotic disease. At present, there are no effective cures for fibrotic disorders. Both agents are currently in phase II trials, pirfenidone for idiopathic pulmonary fibrosis (IPF) and relaxin for systemic sclerosis.
openaire +1 more source
Human Relaxin-2 Fusion for the Treatment of Heart Failure
Journal of Molecular and Cellular Cardiology, 2018Weidong Hao +17 more
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Relaxin and its role in the development and treatment of fibrosis
Translational Research, 2009Robert G Bennett
exaly
Responses of GPCR135 to Human Gene 3 (H3) Relaxin in CHO-K1 Cells Determined by Microphysiometry
Annals of the New York Academy of Sciences, 2005Ross Bathgate +2 more
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Relaxin: Review of Biology and Potential Role in Treating Heart Failure
Current Heart Failure Reports, 2010Marco Metra, John R Teerlink, Gad Cotter
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