Results 71 to 80 of about 11,028 (173)

Regional Functional Molecular Profiles Within the Mammalian Cortex: A Commentary on Limbic Mesocortex

Journal of Comparative Neurology, Volume 534, Issue 8, August 2026.
Two lateral mouse brain sagittal sections labeled, respectively, for Lypd1 (A) and Kcnab3 (B). (A) Lypd1 labels positively cortical Layers 2 and 5 (less heavily), but only at limbic mesocortical sites, forming the limbic ring that separates the unlabeled isocortex (IsoCx) from the unlabeled hippocampal and olfactory allocortex (Hi, Sub, ERh; OlfCx ...
Luis Puelles, Elena Garcia‐Calero
wiley   +1 more source

Relaxin-3 null mutation mice display a circadian hypoactivity phenotype

, 2012
Characterizing the neurocircuits and neurotransmitters that underlie arousal and circadian sleep/wake patterns is an important goal of neuroscience research, with potential implications for understanding human mental illnesses, such as major depression ...
SW Sutton (14876671), AL Gundlach (14448708), Craig Smith (13065255), IT Hosken (14876668), AJ Lawrence (5578280)   +4 more
core  

Integrated Network Analysis Suggests an miR‐21/MMP/VEGF‐Associated Regulatory Axis in Gastric Cancer

Cancer Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background, Aims Gastric cancer (GC) pathogenesis involves complex molecular interactions that remain incompletely understood at a biological systems level. While microRNA‐21 (miR‐21), matrix metalloproteinases (MMPs), and vascular endothelial growth factor (VEGF) have been individually implicated in GC, their integrated role as a coordinated ...
Fatemeh Babajani, Hadi Mozafari
wiley   +1 more source

Comparative distribution of relaxin-3 inputs and calcium-binding protein-positive neurons in rat amygdala

Frontiers in Neuroanatomy, 2016
The neural circuits involved in mediating complex behaviors are being rapidly elucidated using various newly developed and powerful anatomical and molecular techniques, providing insights into the neural basis for anxiety disorders, depression, addiction,
Fabio N Santos, Celia W Pereira, Ana M Sanchez-perez, Marcos eOtero, Sherie K Ma, Andrew L Gundlach, Andrew L Gundlach, Francisco E Olucha-Bordonau   +7 more
doaj   +1 more source

A Mechanistic Review of Environmental Stressor to Decode Their Effect on Congenital Malformations: A Developmental Toxicity

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 8, August 2026.
Environmental toxicants may disrupt developmental pathways via strong molecular docking interactions with hub FGF proteins (FGF9 and FGF4) like dibenzo‐p‐dioxin (−7.2 kcal/mol) at the ASN146 residue of FGF9, driving congenital malformations as revealed by PPI networks and toxicity profiling.
Adarsh Kumar Shukla, Rashmi Mahajan, Anuj Kumar Tyagi, Kamendra Swaroop   +3 more
wiley   +1 more source

Relaxin-3 systems in the brain--the first 10 years

, 2011
The relaxin-3 gene was identified in 2001 by searching the human genome database for homologues of the relaxin hormone, and was subsequently discovered to encode a highly conserved neuropeptide in mammals and lower species.
PJ Ryan (7940525), S Ma (7710638), AL Gundlach (14448708), Craig Smith (13065255), IT Hosken (14876668)   +4 more
core  

Immunohistochemical localization of relaxin in human prostate.

, 1989
We identified relaxin in human male prostate by use of an anti-human relaxin analogue polyclonal antibody and the avidin-biotin-immunoperoxidase method.
J Lechago, X S Wang, R S Swerdloff, P D Johnston, R Z Sokol   +4 more
core   +1 more source

Relaxin-3 receptor (Rxfp3) gene knockout mice display reduced running wheel activity: implications for role of relaxin-3/RXFP3 signalling in sustained arousal

, 2015
Anatomical and pharmacological evidence suggests the neuropeptide, relaxin-3, is the preferred endogenous ligand for the relaxin family peptide-3 receptor (RXFP3) and suggests a number of putative stress- and arousal-related roles for RXFP3 signalling ...
SW Sutton (14876671), AL Gundlach (14448708), Craig Smith (13065255), IT Hosken (14876668)   +3 more
core  

Relaxin in endometriosis

, 2009
Endometriosis is an important contributing factor to chronic pelvic pain and infertility. Matrix metalloproteinases (MMPs) and vascular endothelial growth factor (VEGF) have each been implicated in the establishment of endometriotic lesions.
MORELLI, S. S., FLORIO, P., LUISI, S., WEISS, G., PETRAGLIA, F., GOLDSMITH, L. T.   +5 more
core   +1 more source

RELAXIN-3/RXFP3 signalling promotes motivational drive and stress resilience in mice

, 2015
RELAXIN-3/RXFP3 signalling promotes motivational drive and stress resilience in ...
E Timofeeva (13357596), D Denton (13594021), A Gundlach (13646296), A Walker (9855653), I Hosken (13748437), M McKinley (13594015), Craig Smith (13065255), B Chua (13748431), C Zhang (2567170), A Lawrence (9877598)   +9 more
core