Results 81 to 90 of about 11,028 (173)
Elucidation of relaxin-3 binding interactions in the extracellular loops of RXFP3
Frontiers in Endocrinology, 2013 Relaxin-3 is a highly conserved neuropeptide in vertebrate species and binds to the Class A G protein-coupled receptor RXFP3. Relaxin-3 is involved in a wide range of behaviours, including feeding, stress responses, arousal and cognitive processes and ...
Ross eBathgate +10 more
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This Hormone Has Been Relaxin' Too Long!
, 2002 © 2002 American Association for the Advancement of ScienceThe hormone relaxin is known to be important in pregnancy but its receptor has long remained elusive.
Ivell, R.
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Reproductive Biology and Endocrinology, 2007 Background Relaxin is the endogenous ligand of the G-protein coupled receptor RXFP1, previously known as LGR7. In humans relaxin can also activate, but with lower affinity, the closely related receptor for the insulin-like peptide from Leydig cells ...
Porto Catarina S +6 more
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, 2017 Relaxin-3/RXFP3 signalling is proposed to be involved in the neuromodulatory control of arousal- and stress-related neural circuits. Furthermore, previous studies in rats have led to the proposal that relaxin-3/RXFP3 signalling is associated with ...
JS Bains (14876695) +4 more
core
RELAXIN-3/RXFP3 systems and central stress- and anxiety-related circuits in mice
, 2015 RELAXIN-3/RXFP3 systems and central stress- and anxiety-related circuits in ...
E Timofeeva (13357596) +6 more
core
Peptide hormone relaxin: from bench to bedside
, 2018 The peptide hormone relaxin has numerous roles both within and independent of pregnancy and is often thought of as a “pleiotropic hormone.” Relaxin targets several tissues throughout the body, and has many functions associated with extracellular matrix ...
Sarah A. Marshall +11 more
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, 2014 Animal and clinical studies of gene-environment interactions have helped elucidate the mechanisms involved in the pathophysiology of several mental illnesses including anxiety, depression, and schizophrenia; and have led to the discovery of improved ...
AW Walker (14876659) +6 more
core
Relaxin-3 receptor (Rxfp3) gene deletion reduces operant sucrose- but not alcohol-responding in mice
, 2015 The pervasive use of refined sugars in highly accessible, palatable foods and persistent exposure to reinforcing food-associated cues has contributed to overconsumption of sugar-rich diets and the current obesity epidemic in Western society.
AW Walker (14876659) +3 more
core
Relaxin-3 receptor (RXFP3) signalling mediates stress-related alcohol preference in mice
, 2015 Stressful life events are causally linked with alcohol use disorders (AUDs), providing support for a hypothesis that alcohol consumption is aimed at stress reduction. We have previously shown that expression of relaxin-3 mRNA in rat brain correlates with
AW Walker (14876659) +6 more
core
Endometrial expression of relaxin and relaxin receptor in endometriosis
, 2010 Our studies demonstrate significantly lower expression of relaxin and its receptor in ectopic endometriotic tissues than their expression in eutopic endometrium and in endometrium from normal controls.
MORELLI, S. S. +13 more
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