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Imipenem/relebactam pharmacokinetics in critically ill patients supported on extracorporeal membrane oxygenation

Journal of Antimicrobial Chemotherapy
Abstract Background Extracorporeal membrane oxygenation (ECMO) is a life-saving modality but has the potential to alter the pharmacokinetics (PK) of antimicrobials. Imipenem/cilastatin/relebactam is an antibiotic with utility in treating certain multi-drug resistant Gram-negative infections.
Andrew J Fratoni   +4 more
openaire   +2 more sources

Imipenem/cilastatina/relebactam en infecciones por bacterias gramnegativas

Panorama Actual del Medicamento
Relebactam es un nuevo inhibidor de betalactamasas con estructura no betalactámica, con capacidad para inhibir betalactamasas de tipo A y C, pero no B y D. Sin actividad antibacteriana significativa, la función de relebactam en la combinación con imipenem y cilastatina consiste en restituir la actividad bactericida de imipenem cuando ésta se ve ...
openaire   +1 more source

Biomerieux Imipenem Relebactam IVD

Biomedical Safety & Standards, 2021
openaire   +1 more source

Relebactam. Beta-lactamase inhibitor

Drugs of the Future, 2015
openaire   +1 more source

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