Results 51 to 60 of about 2,268,235 (274)

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

FEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan, Lu Qi, Pierre Zalloua   +2 more
wiley   +1 more source

TOWARDS RELIABLE CALCULATIONS OF THE CORRELATION FUNCTION [PDF]

International Journal of Modern Physics E, 2007
The correlation function of two identical pions interacting via Coulomb potential is computed for a general case of anisotropic particle's source of finite life time. The effect of halo is taken into account as an additional particle's source of large spatial extension.
Stanisław Mrówczyński, Radosław Maj
openaire   +3 more sources

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

FEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer, Matheus Felipe Santos, Maurício Mazzine Filho, Gabriela Oliveira Castro, Agustín Hernández, Manoel Aparecido Peres, Alejandro Miguel Katzin, Marcell Crispim   +7 more
wiley   +1 more source

Reliability of genetic networks is evolvable

, 2007
Control of the living cell functions with remarkable reliability despite the stochastic nature of the underlying molecular networks -- a property presumably optimized by biological evolution.
A. Wagner, Stefan Bornholdt, Stefan Braunewell   +2 more
core   +1 more source

Decline and repair, and covariate effects [PDF]

, 2015
The failure processes of repairable systems may be impacted by operational and environmental stress factors. To accommodate such factors, reliability can be modelled using a multiplicative intensity function.
Andersen, Dekker, Doyen, Guo, Han, Jiang, Kalbfleisch, Kijima, Kijima, Kirschenmann, Lam, Malik, Meyer, Nakagawa, Philip Scarf, Scarf, Shaomin Wu, Wang, Wu, Wu, Xiang, Zhong   +21 more
core   +3 more sources

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Exploring the Differential Geometry of Reliability Function: Insights from Lifetime Weibull Distributions Under Neutrosophic Environment [PDF]

Neutrosophic Sets and Systems
This paper characterizes a set N as a two-dimensional surface marked by 𝑅 + × 𝑅 + and demonstrates its properties as a topological 2-reliability manifold and a differential reliability manifold.
Nada Mohammed Abbas, Ghazi Abdullah, Ahmed Hadi Hussain   +2 more
doaj   +1 more source

Fuzzy Reliability Theory Based on Membership Function [PDF]

International Journal of Mathematical, Engineering and Management Sciences, 2016
In this study, it is considered that the shape of membership function and the values of parameters are arbitrary, hence reliability parameters will be arbitrary, and some data are even absurd from the point of view of real life practice. An applied fuzzy
Shshank Chaube, S. B. Singh
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Bayesian Estimation of Reliability of the Electronic Components Using Censored Data from Weibull Distribution: Different Prior Distributions

International Journal of Industrial Engineering and Production Research, 2014
The Weibull distribution has been widely used in survival and engineering reliability analysis. In life testing experiments is fairly common practice to terminate the experiment before all the items have failed, that means the data are censored.
fernando antonio Moala
doaj