Results 91 to 100 of about 33,863 (342)

Abnormal metabolic network activity in REM sleep behavior disorder [PDF]

, 2014
OBJECTIVE: To determine whether the Parkinson disease-related covariance pattern (PDRP) expression is abnormally increased in idiopathic REM sleep behavior disorder (RBD) and whether increased baseline activity is associated with greater individual risk ...
+1 additional author, Dhawan, V., Eidelberg, D., Feigin, A., Gagnon, J. F., Holtbernd, F., Ma, Y., Montplaisir, J., Postuma, R. B., Soucy, J. P., Tang, C. C.   +10 more
core   +3 more sources

Progranulin Mutation Manifesting as Parkinson Disease: A Case Series from the PADUA‐CESNE Cohort

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Mutations in progranulin (GRN) are associated with frontotemporal dementia, although a Parkinson disease (PD) phenotype is uncommon, especially in young patients. Cases We report three subjects from the PADUA‐CESNE cohort, meeting diagnostic criteria for PD, with onset under age 55.
Giulia Bonato, Marta Campagnolo, Aron Emmi, Valentina Misenti, Tommaso Carrer, Carmelo Fogliano, Leonardo Salviati, Miryam Carecchio, Angelo Antonini   +8 more
wiley   +1 more source

Motor Cortex Disinhibition Correlates with Olfactory Dysfunction in Parkinson's Disease

Movement Disorders, EarlyView.
Abstract Background Motor cortex disinhibition, as measured by impaired short‐interval intracortical inhibition (SICI) using transcranial magnetic stimulation (TMS), is a well‐established feature of Parkinson's disease (PD). However, its substantial variability among patients remains unexplained, prompting questions about its origin, clinical relevance,
Claudia Ammann, Cristina Pagge, Emmanuelle Wilhelm, Chiara Galletti, Tamara Jimenez‐Castellanos, Michele Matarazzo, Agustina Ruiz‐Yanzi, Carmen Gasca‐Salas, Raul Martínez‐Fernández, Fernando Alonso‐Frech, Antonio Oliviero, José A. Obeso, Guglielmo Foffani   +12 more
wiley   +1 more source

Duloxetine-induced rapid eye movement sleep behavior disorder: a case report

BMC Psychiatry, 2017
Background Tricyclic antidepressants and selective serotonin reuptake inhibitors have been reported to induce the symptoms of rapid eye movement (REM) sleep behavior disorder (RBD) or to exacerbate REM sleep without atonia.
Lu Tan, Junying Zhou, Linghui Yang, Rong Ren, Ye Zhang, Taomei Li, Xiangdong Tang   +6 more
doaj   +1 more source

Cholinergic System Changes in Dopa‐Unresponsive Freezing of Gait in Parkinson's Disease

Movement Disorders, EarlyView.
Abstract Background Freezing of gait (FoG) is a debilitating mobility disturbance that becomes increasingly resistant to dopaminergic pharmacotherapies with advancing Parkinson's disease (PD). The pathophysiology underlying the response of FoG to dopaminergic treatment is poorly understood.
Kelvin L. Chou, Prabesh Kanel, Miriam van Emde Boas, Stiven Roytman, Giulia Carli, Roger L. Albin, Nicolaas I. Bohnen   +6 more
wiley   +1 more source

The impact of sleep quality on cognitive functioning in Parkinson's disease [PDF]

, 2011
In healthy individuals and those with insomnia, poor sleep quality is associated with decrements in performance on tests of cognition, especially executive function. Sleep disturbances and cognitive deficits are both prevalent in Parkinson's disease (PD).
Bogdanova, Y., Cronin-Golomb, Alice, McNamara, P., Neargarder, S., Stavitsky, K.   +4 more
core   +2 more sources

Distinct Longitudinal Clinical‐Neuroanatomical Trajectories in Parkinson's Disease Clinical Subtypes: Insight toward Precision Medicine

Movement Disorders, EarlyView.
ABSTRACT Background Parkinson's disease (PD) varies widely across individuals in clinical manifestations and course of progression. Identification of distinct biological subtypes could explain this heterogeneity, identify its pathophysiology, and predict disease progression. Objectives Our aim was to compare longitudinal clinical trajectories and brain
Seyed‐Mohammad Fereshtehnejad, Roqaie Moqadam, Houman Azizi, Ronald B. Postuma, Mahsa Dadar, Anthony E. Lang, Connie Marras, Yashar Zeighami   +7 more
wiley   +1 more source

REM sleep behavior disorder: From dreams to neurodegeneration

Neurobiology of Disease, 2012
REM sleep behavior disorder is a unique parasomnia characterized by dream enactment behavior during REM sleep. Unless triggered by pharmacologic agents such as antidepressants, it is generally related to damage of pontomedullary brainstem structures ...
Ronald B. Postuma, Jean-Francois Gagnon, Jacques Y. Montplaisir   +2 more
doaj  

Electrophysiological Evaluation in Identifying Unique Sleep Features Among Anti-LGI1 Encephalitis Patients During Active and Recovery Phase

Nature and Science of Sleep, 2021
Xiaoyun Liu,1,* Liling Yang,1,* Yuxiang Han,1 Jingjing Xu,2 Zaiying Pang,1 Yifeng Du,1 Yabo Feng,1,* Youting Lin1,* 1Department of Neurology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan City, Shandong Province ...
Liu X, Yang L, Han Y, Xu J, Pang Z, Du Y, Feng Y, Lin Y   +7 more
doaj  

Identification of GGC Repeat Expansions in ZFHX3 among Chilean Movement Disorder Patients

Movement Disorders, EarlyView.
Abstract Background Hereditary ataxias are genetically diverse, yet up to 75% remain undiagnosed due to technological and financial barriers. The GGC repeat expansion in ZFHX3, responsible for spinocerebellar ataxia type 4 (SCA4), has only been described in individuals of Northern Europeandescent.
Paula Saffie‐Awad, Abraham Moller, Kensuke Daida, Pilar Alvarez Jerez, Zhongbo Chen, Zachary B. Anderson, Mariam Isayan, Kimberly Paquette, Sophia B. Gibson, Madison Fulcher, Abigail Miano‐Burkhardt, Laksh Malik, Breeana Baker, Paige Jarreau, Henry Houlden, Mina Ryten, Bida Gu, Mark J.P. Chaisson, Danny E. Miller, Pedro Chaná‐Cuevas, Cornelis Blauwendraat, Andrew B. Singleton, Kimberley J. Billingsley   +22 more
wiley   +1 more source