Results 81 to 90 of about 33,863 (342)
The Association of Psoriasis With Sleep Disorders in a Diverse National Cohort
ABSTRACT Background Higher prevalence of sleep disorders is seen in persons with psoriasis (PsO). However, the extent to which sleep conditions are linked to PsO severity, particularly across diverse populations, remains unknown. Bridging this knowledge gap is vital for developing comprehensive, equitable and personalized care strategies. Objectives We
Michael J. Diaz+6 more
wiley +1 more source
Parasomnias and Antidepressant Therapy: A Review of the Literature [PDF]
There exists a varying level of evidence linking the use of antidepressant medication to the parasomnias, ranging from larger, more comprehensive studies in the area of REM sleep behavior disorder to primarily case reports in the NREM parasomnias.
Kierlin, Lara, Littner, Michael R.
core +3 more sources
Sleep pattern disruption, specifically REM sleep behavior disorder (RBD), is a major nonmotor cause of disability in PD. Understanding the pathophysiology of these sleep pattern disturbances is critical to find effective treatments.
Quynh Vo+4 more
doaj +1 more source
Being Prodromal: Current Criteria in the Context of Isolated REM Sleep Behavior Disorder
ABSTRACT Background Isolated REM sleep behavior disorder (iRBD) indicates an early α‐synucleinopathy with approximately 90% of individuals pheno‐converting to Parkinson's disease (PD), dementia with Lewy bodies (DLB), or multiple system atrophy (MSA). Recently, prodromal disease definitions (pPD, pDLB, pMSA) have been introduced.
Anja Ophey+5 more
wiley +1 more source
Abstract Background The lived experience of Parkinson's disease (PD) includes motor and non‐motor symptoms. There is a need to capture the earliest patient experiences in a sensitive and reliable manner for the successful development of interventions that may delay clinical progression in PD.
Joseph Saade+3 more
wiley +1 more source
Abstract Background Dopaminergic neuron depletion in the substantia nigra (SN) and the pathological aggregation of α‐synuclein are the neuropathological hallmarks of Parkinson's disease (PD). Objectives This study aimed to investigate the association between the polygenic risk score for PD (PD‐PRS) and transcranial sonography (TCS)‐measured SN ...
Mart Kals+11 more
wiley +1 more source
Parasomnias: Diagnosis, Classification and Clinical Features [PDF]
Parasomnias, as described in the recent second edition of the International Classification of Sleep Disorders, are “undesirable physical events or experiences” occurring during sleep transition, during arousal from sleep, or within the sleep period ...
Fatma Ozlem Orhan, Deniz Tuncel
doaj
The Gut‐Brain Axis in Parkinson disease: Emerging Concepts and Therapeutic Implications
Abstract Background The gut‐brain axis, i.e. the bidirectional communication system between the gut and the brain, has become of central importance in Parkinson disease (PD) research over the past 20 years. Aims We aimed to describe the milestones of the gut‐brain axis research in PD and the development of theories proposing the involvement of the ...
Elisa Menozzi+2 more
wiley +1 more source
Rest–Activity Disturbances Correlate with Core Features in Dementia with Lewy Bodies
Abstract Background Sleep–wake disturbances are a clinically important and poorly studied feature of dementia with Lewy bodies (DLB) due to the challenges of in‐laboratory polysomnography in this population. Objectives To compare rest–activity rhythms in DLB, Parkinson's disease (PD), and age‐matched controls using home‐based wrist actigraphy and ...
Jack Anderson+7 more
wiley +1 more source
Lewy Body Dementia Research in Latin America: A Scoping Review
Abstract Background Dementia research in Latin America (LA) has primarily focused on Alzheimer's Disease and Frontotemporal Dementia, while Lewy body dementia (LBD) has been largely forgotten. Objective We aimed to review the available evidence on LBD in LA, offering a comprehensive perspective for understanding the lack of reports and the unique ...
Carlos Cano‐Gutiérrez+31 more
wiley +1 more source