Results 71 to 80 of about 37,793 (186)

Efficacy and Safety of Remdesivir in Hospitalized Pediatric COVID-19: A Retrospective Case-Controlled Study

, 2023
Ahmed Khalil,1 Asmaa Mohamed,1 Manasik Hassan,2 Samar Magboul,2 Hossamaldein Ali,1 Ahmed Salah Elmasoudi,1 Khaled Ellithy,3 Mohammad Qusad,2 Abdulla Alhothi,2 Eman Al Maslamani,4 Mohammed Al Amri,5 Ashraf Soliman5 1Section of Pediatric Clinical Pharmacy,
Ali H, Alhothi A, Hassan M, Al Amri M, Khalil A, Mohamed A, Elmasoudi AS, Soliman A, Magboul S, Ellithy K, Qusad M, Al Maslamani E   +11 more
core  

Phase IIB, Randomized, Double‐Blind, Placebo‐Controlled Clinical Trial of Intravenous Defibrotide for the Prevention and Treatment of Respiratory Distress and Cytokine Release Syndrome in COVID‐19

European Journal of Haematology, EarlyView.
ABSTRACT Introduction Endothelial dysfunction is key in COVID‐19 pathogenesis. This randomized, double‐blind phase IIb trial investigated continuous intravenous infusion of defibrotide in patients hospitalized with SARS‐CoV‐2 infection and respiratory failure.
Ruben Jara Rubio, Antonio José Martinez‐Mellado, Jonathan Kiwitt‐Cárdenas, José G. Clavel, Bartolomé García‐Perez, Pedro Castro, Maribel Diaz‐Ricart, Andrés Carrillo‐Alcaraz, Amparo López‐Bernús, Enrique Bernal Morell, Aychel Roura, Sonia Marín, Francisco‐José Ruiz‐López, Elena Solana‐Martinez, Domingo Martinez‐Baño, Carlos L. Albacete Moreno, Enriqueta Andreu Soler, Adrián Tellez Santoyo, Sara Fernández Méndez, Jose A. Noguera Velasco, Iria Cebreiros Lopez, Andrés Parrilla, Alberto Espuny‐Miró, David García‐Bernal, Miguel Blanquer, Andrés Sánchez‐Salinas, Francisca Iniesta, Cristina Hernandez Garcia, Manuel Muro, Alfredo Minguela Puras, Antonio Moreno‐Docón, Alberto M. Torres‐Cantero, Maria Munoz Garcia, Manuel Serrano, Massimo Iacobelli, Carmelo Carlo‐Stella, Lee‐Jen Wei, Paul G. Richardson, José M. Moraleda   +38 more
wiley   +1 more source

Association Between Use of Remdesivir and Bradycardia

, 2022
Remdesivir received the first emergency use authorization from the FDA for the treatment of COVID-19. Multiple adverse drug reactions (ADR) have been reported since its approval in October 2020.
Umeukeje, Gibret
core  

Impact of remdesivir use on budget.

, 2022
Impact of remdesivir use on budget.
Guillaume Béraud (2558941), Jean-François Timsit (58724), Henri Leleu (449520)   +2 more
core   +1 more source

Comparative assessment of favipiravir and remdesivir against human coronavirus NL63 in molecular docking and cell culture models

Scientific Reports, 2021
Human coronavirus NL63 (HCoV-NL63) mainly affects young children and immunocompromised patients, causing morbidity and mortality in a subset of patients.
Yining Wang, Pengfei Li, Sajjan Rajpoot, Uzma Saqib, Peifa Yu, Yunlong Li, Yang Li, Zhongren Ma, Mirza S. Baig, Qiuwei Pan   +9 more
doaj   +1 more source

Guideline for the Diagnosis and Management of Heritable IFNAR1 Deficiency in Oceania

Journal of Paediatrics and Child Health, EarlyView.
ABSTRACT Autosomal recessive interferon alpha and beta receptor subunit 1 (IFNAR1) deficiency is a rare and heritable inborn error of immunity (IEI) predisposing individuals to severe and life‐threatening viral infections. It is more common in people of Western Polynesian ancestry, with estimates of around one in six thousand live births affected, due ...
Cecilia Verryt, Paul Gray, Peter McNaughton, Jane Peake, Melanie Wong, George Aho, Emma Best, Maia Brewerton, Flora Lutui, Litara Esera Tulifau, Rebecca Qin, Satupa‘itea Viali, Petine White, Andrew Wood, See‐Tarn Woon, Theresa Cole, Alberto Pinzon Charry, Kuang‐Chih Hsiao   +17 more
wiley   +1 more source

Remdesivir treatment for patients with moderate to severe COVID-19

, 2022
Background/aim: Remdesivir, which was first developed for the treatment of Ebola disease but failed to meet expectations, has become hope in the fight against the COVID-19 pandemic. This study aimed to evaluate risk factors for mortality and prognosis of
Tabak, Fehmi, Yasar, Kadriye Kart, Batirel, Ayse, TELLİ DİZMAN, GÜLÇİN, Cagatay, Arif Atahan, HASANOĞLU, İMRAN, Gül, Ahmet, Sevgi, Dilek Yıldız, Bozkurt, Ilkay, Alp, Emine, Guner, Rahmet, KANAT, FİKRET, Eren, Esma, Senoglu, Sevtap, KARAALİ, RIDVAN, KAZAK, ESRA, Celikbas, Aysel, ÜNAL, SERHAT, Erdinc, Sebnem, Sevgi, Dilek Yildiz, PULLUKÇU, HÜSNÜ, Karaali, Rıdvan, Celik, Ilhami, Dizman, Gülçin Telli   +23 more
core   +1 more source

Remdesivir-induced severe hypoglycemia in an elderly man without diabetes: a case report

Journal of Pharmaceutical Health Care and Sciences
Background Remdesivir is recommended to treat hospitalized patients with coronavirus disease 2019 (COVID-19). Remdesivir is known to affect glucose metabolism in individuals with and without diabetes.
Yasunori Nagano, Hisae Aoki, Juri David, Naoko Iwahashi Kondo, Makimi Aizawa, Toshiyuki Sumita, Yuki Hamada, Yuki Yamamoto, Kaoru Yamada   +8 more
doaj   +1 more source

Cost-effectiveness of remdesivir for the treatment of hospitalized patients with COVID-19: a systematic review

Infectious Diseases of Poverty, 2023
Background Remdesivir is being studied and used to treat coronavirus disease 2019 (COVID-19). This study aimed to systematically identify, critically evaluate, and summarize the findings of the studies on the cost-effectiveness of remdesivir in the ...
Aziz Rezapour, Zahra Behroozi, Mostafa Nasirzadeh, Mohsen Rezaeian, Mohammad Barzegar, Mahsa Tashakori-Miyanroudi, Abdollah Sayyad, Aghdas Souresrafil   +7 more
doaj   +1 more source

Serine Protease Inhibitory Activity of Kampo Medicines: One of the Mechanisms Against Cold Syndrome

Traditional &Kampo Medicine, Volume 13, Issue 2, August 2026.
Serine protease inhibitory activity is involved in the mechanism of Kampo medicines used for treating common cold symptoms Ryokankyomishingeninto exhibited serine protease inhibitory activity in vitro and in vivo. Ryokankyomishingeninto showed anti‐SARS‐CoV‐2 activity in VeroE6/TMPRSS2 cells. ABSTRACT Aim Serine proteases play a key role in coronavirus
Yukiko Matsuo, Reina Akaiwa, Miku Yanagioka, Mishizu Kikuchi, Yuuna Kawahara, Takuma Yoshida, Hidemasa Nakaminami, Niro Inaba, Yoshihiro Mimaki   +8 more
wiley   +1 more source