Stroke neurovascular responses to exercise: A novel rehabilitation paradigm
Experimental Physiology, EarlyView.Abstract Stroke is a leading cause of long‐term disability, impacting the cerebrovascular, peripheral vascular and neuromotor systems. Characterising vascular responses to exercise post‐stroke offers valuable insights into the impairments that might influence outcomes during neurorehabilitation.
Alicen A. Whitaker‐Hilbig +2 more
wiley +1 more source
The acute and chronic effects of local aerobic exercise on cardiovascular physiology
Experimental Physiology, EarlyView.Abstract Exercise training has beneficial effects for primary and secondary prevention of cardiovascular disease (CVD). Effects of exercise training have typically been studied in the form of whole‐body exercise training, partly driven by the assumption that larger effects of exercise training can be achieved by involving more and larger muscle groups.
Myrthe P. F. van de Ven +3 more
wiley +1 more source
Myocardial protection by ischemic remote conditioning in coronary revascularization
Revista Cubana de Anestesiología y Reanimación, 2019 Introduction: A series of short periods of distant ischemia, prior to the major ischemic event, can limit the myocardial damage produced by ischemia or reperfusion.
Rudy Hernández Ortega +4 more
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Calcium‐activated chloride channels in pericytes and their role in regulating organ blood flow
The Journal of Physiology, EarlyView.Abstract figure legend Pericytes are microvascular mural cells with diverse roles. Contractile pericytes directly regulate local perfusion, while non‐contractile pericytes coordinate upstream vascular contractility via propagating electrical signals.
Paolo Tammaro, Hikaru Hashitani
wiley +1 more source
Mitochondrial oxidative stress, calcium and dynamics in cardiac ischaemia‐reperfusion injury
The Journal of Physiology, EarlyView.Abstract figure legend Heart attack causes ischaemia–reperfusion injury in cardiomyocytes. Mitochondria generate reactive oxygen species (ROS), leading to oxidative stress. High levels of mitochondrial calcium (Ca2+) activate the mitochondrial permeability transition pore (mPTP), and excess ROS levels can lower the Ca2+ required to activate the mPTP ...
Emily Rozich +5 more
wiley +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend Schematic overview of the temporal evolution of the post‐myocardial infarction substrate leading to ventricular tachycardia. Acute ischaemic injury initiates metabolic and electrophysiological disruption, followed by progressive inflammatory, fibrotic and structural remodelling within the infarct border zone.
Mohammed Obeidat +6 more
wiley +1 more source
Remote ischemic conditioning for safe cardioprotection in cardio-oncology? [PDF]
Basic Res CardiolTotzeck M, Rassaf T.
europepmc +1 more source
Hypoxia‐induced vulnerability of the somatosensory nervous system
The Journal of Physiology, EarlyView.Abstract figure legend Sensory neurons are highly energy dependent and rely on sufficient oxygen availability to maintain metabolic stability and effective neurocommunication. Within the somatosensory system, even modest reductions in tissue oxygen tension impair neuronal respiration, forcing a shift toward less efficient metabolic pathways that ...
Jack Corbett, Richard P. Hulse
wiley +1 more source
The role of remote ischemic conditioning in ischemic stroke: neuroprotective mechanisms and future directions. [PDF]
Front ImmunolYu T +11 more
europepmc +1 more source
Insights Into Remote Ischemic Conditioning miRNA Effects on Brain Endothelial Cells During Ischemia-Reperfusion. [PDF]
MicrocirculationStenz KT +6 more
europepmc +1 more source