Results 141 to 150 of about 1,266,306 (262)

Calcium‐activated chloride channels in pericytes and their role in regulating organ blood flow

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Pericytes are microvascular mural cells with diverse roles. Contractile pericytes directly regulate local perfusion, while non‐contractile pericytes coordinate upstream vascular contractility via propagating electrical signals.
Paolo Tammaro, Hikaru Hashitani
wiley   +1 more source

The multicellular environment of the re‐entrant circuit in post‐myocardial infarction ventricular tachycardia: Beyond fibrosis

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Schematic overview of the temporal evolution of the post‐myocardial infarction substrate leading to ventricular tachycardia. Acute ischaemic injury initiates metabolic and electrophysiological disruption, followed by progressive inflammatory, fibrotic and structural remodelling within the infarct border zone.
Mohammed Obeidat   +6 more
wiley   +1 more source

Myocardial protection by ischemic remote conditioning in coronary revascularization

open access: yesRevista Cubana de Anestesiología y Reanimación, 2019
Introduction: A series of short periods of distant ischemia, prior to the major ischemic event, can limit the myocardial damage produced by ischemia or reperfusion.
Rudy Hernández Ortega   +4 more
doaj  

Hypoxia‐induced vulnerability of the somatosensory nervous system

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Sensory neurons are highly energy dependent and rely on sufficient oxygen availability to maintain metabolic stability and effective neurocommunication. Within the somatosensory system, even modest reductions in tissue oxygen tension impair neuronal respiration, forcing a shift toward less efficient metabolic pathways that ...
Jack Corbett, Richard P. Hulse
wiley   +1 more source

CX3CR1 Modulates Migration of Resident Microglia Towards Cortical Laser‐Induced Lesions

open access: yesGlia, Volume 74, Issue 10, October 2026.
CX3CR1 deficiency promotes microglial migration toward CNS injury. Proteomic profiling reveals altered RHO‐mediated cytoskeletal signaling, while in vivo two‐photon imaging demonstrates increased process extension, velocity, and accumulation of Cx3cr1‐deficient microglia at lesion sites. ABSTRACT Microglia are innate immune cells of the central nervous
Jens Wagner   +13 more
wiley   +1 more source

Remote Ischemic Conditioning in Patients With Acute Ischemic Stroke Ineligible for Recanalization Therapies: A Phase II Trial. [PDF]

open access: yesStroke Vasc Interv Neurol
Diamanti S   +23 more
europepmc   +1 more source

Simultaneous 3‐D Adiabatic T1ρ, T2*, and Quantitative Susceptibility Mapping for Characterization of Myocardial Infarction in Ex Vivo Mouse

open access: yesNMR in Biomedicine, Volume 39, Issue 10, October 2026.
This study combines segmented T1ρ preparation into a 3‐D gradient‐echo sequence for simultaneous quantitative susceptibility, T2*, and T1ρ mapping of infarcted mouse hearts ex vivo. The method enabled assessment of T1ρ and T2* relaxation time maps and magnetic susceptibility, with ischemic regions clearly identified by all contrasts and consistent with
Iida Räty   +6 more
wiley   +1 more source

The role of remote ischemic conditioning in ischemic stroke: neuroprotective mechanisms and future directions. [PDF]

open access: yesFront Immunol
Yu T   +11 more
europepmc   +1 more source

Effects of a Cycling‐Based Aerobic Exercise Program Versus a Resistance and Neuromuscular Exercise Program on Exercise‐Induced Hypoalgesia in Knee Osteoarthritis: A Study Protocol for a Randomized Clinical Trial

open access: yesPhysiotherapy Research International, Volume 31, Issue 4, October 2026.
ABSTRACT Background and Purpose Exercise therapy is a core treatment for knee osteoarthritis (KOA), but the effects of different exercise modalities on endogenous pain modulation remain unclear. This trial will compare a cycling‐based aerobic exercise program with a resistance and neuromuscular exercise program on exercise‐induced hypoalgesia (EIH) in ...
Bruno Ruocco Verengue   +6 more
wiley   +1 more source

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