Results 151 to 160 of about 10,594 (253)

Mitochondrial oxidative stress, calcium and dynamics in cardiac ischaemia‐reperfusion injury

The Journal of Physiology, EarlyView.
Abstract figure legend Heart attack causes ischaemia–reperfusion injury in cardiomyocytes. Mitochondria generate reactive oxygen species (ROS), leading to oxidative stress. High levels of mitochondrial calcium (Ca2+) activate the mitochondrial permeability transition pore (mPTP), and excess ROS levels can lower the Ca2+ required to activate the mPTP ...
Emily Rozich, Ulas Ozkurede, Shanmugasundaram Pakkiriswami, Ryan Gemilere, Samira M. Azarin, Julia C. Liu   +5 more
wiley   +1 more source

Comparative study of the two types of limb remote ischemic per-conditioning on the brain protection

Chinese Journal of Contemporary Neurology and Neurosurgery, 2013
Background Limb remote ischemic per-conditioning (LRPC) has been recognized as an applicable strategy in protecting against cerebral ischemia-reperfusion injury.
Lin-lin MA, Chang-hong REN, Ning LI, Xun-ming JI, Xian-wei ZENG   +4 more
doaj  

In silico predictions of action potential propagation in doxorubicin cardiotoxicity: A parametric study using preclinical 3D magnetic resonance imaging‐based fibrotic left ventricle models

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic overview of the study's methodology and key findings. In a preclinical swine model, doxorubicin administration induced cardiotoxicity, characterized by diffuse fibrotic remodelling and altered electrical function, as assessed by magnetic resonance (MR) imaging and electrophysiological mapping.
Javier Villar‐Valero, Jairo Rodríguez Padilla, Nicolas Cedilnik, Buntheng Ly, Juan F. Gomez, Maxime Sermesant, Mihaela Pop, Beatriz Trenor   +7 more
wiley   +1 more source

Repeated Remote Ischemic Conditioning Protects Against Doxorubicin Cardiotoxicity

JACC. CardioOncology, 2020
Derek J. Hausenloy, MD, PhD, Choon Ta Ng, MD, Jun Hua Chong, MD   +2 more
doaj   +1 more source

The Effect of Remote Ischemic Preconditioning in Diabetic Patients After Elective Percutaneus Coronary Intervention [PDF]

, 2015
Background Experimental and clinical investigations suggest that reperfusion is considered ‘a double-edged sword', as reperfusion would restore oxygen and nutrients supply to the ischemic myocardium to improve its functional recovery, but in the other ...
ANGGRIYANI, N. (NOVI), PARAMITA, D. (DONNA), RIFQI, S. (SODIQUR)   +2 more
core  

Hypoxia‐induced vulnerability of the somatosensory nervous system

The Journal of Physiology, EarlyView.
Abstract figure legend Sensory neurons are highly energy dependent and rely on sufficient oxygen availability to maintain metabolic stability and effective neurocommunication. Within the somatosensory system, even modest reductions in tissue oxygen tension impair neuronal respiration, forcing a shift toward less efficient metabolic pathways that ...
Jack Corbett, Richard P. Hulse
wiley   +1 more source

A Remote Chronic Disease Management Program to Improve Cardiovascular and Metabolic Outcomes in a Diverse Community‐Based Diabetic Population: Study Design of the TAMIS Trial

Journal of Evaluation in Clinical Practice, Volume 32, Issue 4, June 2026.
ABSTRACT Introduction Cardiovascular and cerebrovascular diseases are projected to expand in the coming decades as the main cause of death. This study outlines the escalating burden of cardiovascular diseases in low‐ and middle‐income countries (LMICs), particularly in Latin America (LA), which is expected to surpass that of other high‐population ...
Renato de Carvalho Barros, Andrea Stephanus, José Antonio Barbosa Filho, Evellyn Mariana, Yasmim Botelho, Thaiene M. M. Severino, Robson Conceição Silva, Lucila de Jesus Almeida, Cristiane Koeche, Bruno Gedeon, Mariana Guimarães Souza de Oliveira, Ana Carolina Augusto, Catarina Ferraz, F. Enzo, Gabriela de Lima, Julia Andrade Ibiapina, Giselle Pinto, Sérgio Henrique Rodolpho Ramalho, Ana Claudia C. Nogueira, Andrei C. Sposito, Alessandra M. Campos‐Staffico, Alexandre Anderson S. M. Soares, Luiz Sérgio F. de Carvalho   +22 more
wiley   +1 more source

Nanomaterial‐Mediated Near‐Infrared Photothermal Neuromodulation for Neurologic Disorders

Advanced NanoBiomed Research, Volume 6, Issue 5, May 2026.
This review summarizes how near‐infrared light activates photothermal nanomaterials to enable noninvasive neuromodulation with high spatiotemporal precision. It elucidates the underlying mechanisms, explores targeted therapeutic applications for neurological disorders, discusses integration with optogenetics and biosensors, and addresses future ...
Ting‐Ting Zeng, Yu‐Ge Wang, Ya‐Bing Zhang, Yuan‐Xin Bai, Si‐Tong Lin, Ting‐Ting Zhu, Yan‐Bo Zhou, Wei‐Tong Pan, Pan‐Miao Liu, Jian‐Jun Yang   +9 more
wiley   +1 more source

MXene Quantum Dot–Enabled Biosensing of Metabolic Biomarkers in Cardiovascular and Metabolic Diseases: Biological Context and Translational Perspectives

Engineering Reports, Volume 8, Issue 5, May 2026.
This review provides a comprehensive analysis of MQD‐enabled biosensing platforms with a specific focus on metabolic biomarkers associated with cardiovascular and metabolic diseases. ABSTRACT MXene quantum dots (MQDs) have recently emerged as a versatile class of nanomaterials for biosensing applications, offering unique opportunities for probing ...
Bayan Abdel Majeed, Jasur Rizaev, Zulfiya Nazirova, Ulugbek Axmedov, Haider Abdul Allh, Faris Anad Muhammad, Neeraj Bainsal, Ahmad Mohebi   +7 more
wiley   +1 more source

Diagnostic Accuracy of Cardiovascular Disease Prediction Models: A Systematic Review and Meta‐Analysis of Validation Studies

Health Science Reports, Volume 9, Issue 5, May 2026.
ABSTRACT Background and Aim Cardiovascular diseases (CVD) are widely accepted to be the most serious health care problem in the world. We performed a diagnostic test accuracy systematic review and meta‐analysis to establish the real‐world performance of established CVD risk prediction tools, providing high‐certainty evidence to optimize primary ...
Mohammad Aziz Rasouli, Farid Najafi, Alireza Ansari‐Moghaddam, Bijan Nouri, Farhad Moradpour, Ghobad Moradi, Yousef Moradi   +6 more
wiley   +1 more source