Results 151 to 160 of about 1,356,692 (229)

Remote Ischemic Conditioning on Infarct Growth in Patients With Acute Ischemic Stroke: Subgroup Analysis From the RESIST Trial. [PDF]

open access: yesStroke Vasc Interv Neurol
Lysdahlgaard S   +7 more
europepmc   +1 more source

Hypoxia‐induced vulnerability of the somatosensory nervous system

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Sensory neurons are highly energy dependent and rely on sufficient oxygen availability to maintain metabolic stability and effective neurocommunication. Within the somatosensory system, even modest reductions in tissue oxygen tension impair neuronal respiration, forcing a shift toward less efficient metabolic pathways that ...
Jack Corbett, Richard P. Hulse
wiley   +1 more source

Radiation‐Induced Skin Injury in Cancer Radiotherapy: From Mechanisms to Management

open access: yesAdvanced Oncology, Volume 1, Issue 1, December 2026.
Radiation‐induced skin injuries (RISI) remain a significant challenge faced by cancer patients receiving radiotherapy (RT). This perspective article examines the pathophysiology of RISI and evaluates the currently existing and emerging therapeutic strategies, including stem cell‐derived exosomes and advanced hydrogels.
Zeynep Meral Toutoungi   +3 more
wiley   +1 more source

4‐Methylumbelliferone Restores Age‐Related Changes in Perineuronal Nets, Memory, and Neuroinflammation

open access: yesGlia, Volume 74, Issue 12, December 2026.
Brain aging alters perineuronal nets and neuroinflammation. 4‐methylumbelliferone reversed these aging‐associated changes. 4‐methylumbelliferone reduced age‐associated cognitive decline. Six months of chronic oral treatment was well tolerated. ABSTRACT Aging‐associated cognitive decline is closely linked to dysregulated glial activity and chronic ...
Anda Cimpean   +7 more
wiley   +1 more source

Astrocytic EAAT‐2 Upregulation Supports Neuro‐Axonal Homeostasis in Chronic Inflammatory CNS Lesions

open access: yesGlia, Volume 74, Issue 12, December 2026.
Inflammatory CNS lesions increase extracellular glutamate. Astrocytic EAAT regulation controls glutamate clearance, stabilizes axonal Ca2+ homeostasis, and determines neurite survival during chronic neuroinflammation. ABSTRACT Neuronal loss in multiple sclerosis (MS) is a key factor in the progression of disability.
Luise Reukauf   +9 more
wiley   +1 more source

Astragaloside IV and Ferroptosis Modulation in Pathological Cardiac Hypertrophy: Current Evidence, an Integrative Hypothesis, and Future Directions

open access: yesPharmacology Research &Perspectives, Volume 14, Issue 6, December 2026.
ABSTRACT Pathological cardiac hypertrophy is initially an adaptive response to sustained mechanical, neurohormonal, or metabolic stress; however, it can progress to fibrosis, contractile dysfunction, arrhythmia, and heart failure. Ferroptosis is a type of regulated cell death caused by iron‐dependent phospholipid peroxidation.
Pengbo Liu, Yongzhi Deng
wiley   +1 more source

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