Results 181 to 190 of about 41,992 (300)

Fibrin Inhibits Peripheral Nerve Remyelination by Regulating Schwann Cell Differentiation [PDF]

open access: bronze, 2002
Katerina Akassoglou   +3 more
openalex   +1 more source

Leveraging multiomic approaches to elucidate mechanisms of heterogeneity in Alzheimer's disease: Neuropsychiatric symptoms, co‐pathologies, and sex differences

open access: yesAlzheimer's &Dementia, Volume 21, Issue 8, August 2025.
Abstract The heterogeneity of Alzheimer's disease (AD) is multi‐dimensional, encompassing clinical features such as neuropsychiatric symptoms (NPS), rate of progression, age of onset, comorbidities, and neuropathological features such as co‐pathologies, and represents the diverse outcomes of manifold genetic and environmental risk determinants.
E. Keats Shwab   +21 more
wiley   +1 more source

Imaging myelin degradation in ex vivo prefrontal cortex tissue blocks in Alzheimer's disease and chronic traumatic encephalopathy

open access: yesAlzheimer's &Dementia, Volume 21, Issue 8, August 2025.
Abstract INTRODUCTION Alzheimer's disease (AD) and chronic traumatic encephalopathy (CTE) are tauopathies with gray matter (GM) myelin changes that are challenging to assess with standard imaging. New methods are needed to quantify myelin integrity in autopsy brain tissues. METHODS We used polarization‐sensitive optical coherence tomography (PS‐OCT) to
Anna Novoseltseva   +12 more
wiley   +1 more source

Effectiveness of Autologous Hematopoietic Stem Cell Transplantation versus Alemtuzumab and Ocrelizumab in Relapsing Multiple Sclerosis: A Single Center Cohort Study

open access: yesAnnals of Neurology, Volume 98, Issue 2, Page 294-307, August 2025.
Objective To compare clinical and radiological outcomes among relapsing multiple sclerosis patients treated with autologous hematopoietic stem cell transplantation (AHSCT), alemtuzumab (ATZ), and ocrelizumab (OCR). Methods From a London (UK) hospital‐based observational cohort, modeled data were obtained from 621 relapsing–remitting multiple sclerosis ...
Paolo Antonio Muraro   +16 more
wiley   +1 more source

Lymphotoxin β Receptor (LtβR): Dual Roles in Demyelination and Remyelination and Successful Therapeutic Intervention Using LtβR–Ig Protein [PDF]

open access: hybrid, 2007
Sheila R. Plant   +8 more
openalex   +3 more sources

Advances in Cellular Immune Theranostic Approaches for Glioblastoma: Current Trends and Future Directions

open access: yesCancer Innovation, Volume 4, Issue 4, August 2025.
Glioblastoma (GBM) remains a highly malignant brain tumor with limited treatment efficacy, driving the need for innovative cellular immune theranostic strategies that integrate diagnostic and therapeutic approaches. Recent advances in cellular immunotherapy for GBM include chimeric antigen receptor (CAR)‐T/NK cells, macrophage‐based therapies ...
Ying Gong   +14 more
wiley   +1 more source

SIRT6 modulates lesion microenvironment in LPC induced demyelination by targeting astrocytic CHI3L1

open access: yesJournal of Neuroinflammation
Demyelination occurs widely in the central nervous system (CNS) neurodegenerative diseases, especially the multiple sclerosis (MS), which with a complex and inflammatory lesion microenvironment inhibiting remyelination.
Jingyi Du   +12 more
doaj   +1 more source

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