Results 1 to 10 of about 914,562 (192)

Renal cancer

open access: yesThe Lancet, 2016
The diagnosis and management of renal cell carcinoma have changed remarkably rapidly. Although the incidence of renal cell carcinoma has been increasing, survival has improved substantially. As incidental diagnosis of small indolent cancers has become more frequent, active surveillance, robot-assisted nephron-sparing surgical techniques, and minimally ...
Capitanio Umberto, MONTORSI , FRANCESCO
  +10 more sources

Safety, activity, and pharmacokinetics of camrelizumab in advanced Asian melanoma patients: a phase I study

open access: yesBMC Cancer, 2022
Background Anti-programmed cell death receptor-1 (PD-1) monotherapy is the standard treatment for metastatic melanoma in current. Camrelizumab is a humanized IgG4 anti-PD-1 monoclonal antibody whose safety and efficacy have not been reported in advanced ...
Li Zhou   +17 more
doaj   +1 more source

Chemotherapy combined with antiangiogenic drugs as salvage therapy in advanced melanoma patients progressing on PD-1 immunotherapy

open access: yesTranslational Oncology, 2021
Background: This study aimed to evaluate the effect of salvage therapy with nab-paclitaxel (nab-p) or temozolomide (TMZ) combined with antiangiogenic drugs in programmed death 1 (PD-1) inhibitor-resistant patients with unresectable metastatic melanoma ...
Xuan Wang   +13 more
doaj   +1 more source

Renal Cancer

open access: yesUrologiia (Moscow, Russia : 1999)
Pandey J, Syed W.
europepmc   +5 more sources

Surgical Outcomes of Vaginal or Cervical Melanoma

open access: yesFrontiers in Surgery, 2022
Objective: To evaluate the effectiveness of radical resection compared with non-radical resection for vaginal or cervical melanoma.Methods: We retrospectively analysed the clinical data of post-operative patients with primary lower genital tract melanoma
Hui Tian   +18 more
doaj   +1 more source

What do end-users want to know about managing the performance of healthcare delivery systems? Co-designing a context-specific and practice-relevant research agenda

open access: yesHealth Research Policy and Systems, 2021
Background Despite increasing interest in joint research priority-setting, few studies engage end-user groups in setting research priorities at the intersection of the healthcare and management disciplines.
Jenna M. Evans   +8 more
doaj   +1 more source

Radiological dynamics and SITC-defined resistance types of advanced melanoma during anti-PD-1 monotherapy: an independent single-blind observational study on an international cohort

open access: yesJournal for ImmunoTherapy of Cancer, 2021
Background Although the Society for Immunotherapy of Cancer (SITC) Immunotherapy Resistance Taskforce recently defined primary and secondary resistance to anti-programmed cell death protein 1 (anti-PD-1) therapy, there is lack of real-world data ...
Xiaoling Yang   +16 more
doaj   +1 more source

miR-let-7b and miR-let-7c suppress tumourigenesis of human mucosal melanoma and enhance the sensitivity to chemotherapy

open access: yesJournal of Experimental & Clinical Cancer Research, 2019
Background Mucosal melanoma with poor prognosis is a common histopathologic subtype of melanoma among Chinese and other Asian peoples. Regulated microRNAs (miRNAs) have been reported as oncogenes or tumour suppressors in melanoma.
Huan Tang   +14 more
doaj   +1 more source

Phase 1 trial of vorolanib (CM082) in combination with everolimus in patients with advanced clear-cell renal cell carcinoma

open access: yesEBioMedicine, 2020
Background: Vorolanib (X-82, CM082) is a multi-target tyrosine kinase inhibitor. This study aimed to evaluate the tolerability, safety, pharmacokinetics and antitumor activities of vorolanib plus everolimus (an inhibitor of mammalian target of rapamycin).
Xinan Sheng   +16 more
doaj   +1 more source

Incidental radiological finding of a renal tumour leading to the diagnosis of Birt-Hogg-Dubé syndrome [PDF]

open access: yes, 2011
Birt-Hogg-Dubé (BHD) syndrome is a rare autosomal dominant condition characterised by benign tumours of the hair follicle, renal cancer, pulmonary cysts and spontaneous pneumothorax.
Dewilde, Dirk   +5 more
core   +1 more source

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