Results 31 to 40 of about 914,661 (291)

Preliminary study on the role of the C5orf46 gene in renal cancer

Translational Oncology, 2022
Background: C5orf46 has been found to have antibacterial and anti-inflammatory effects via sequencing and microarray technologies, but its effects on cancer are unclear.
Ming Ma, Zhicheng Zhang, Yifu Liu, Zhilong Li, Shengqiang Fu, Qiang Chen, Siyuan Wang   +6 more
doaj   +1 more source

Expression and regulatory effects on cancer cell behavior of NELL1 and NELL2 in human renal cell carcinoma [PDF]

, 2015
We thank Professors Michael Rehli, Yoshiaki Ito, and Kristian Helin for gifting plasmids, Dr. Alasdair MacKenzie (University of Aberdeen) for helpful discussion, and Mr. Takashi Mizukami, Ms. Ryoko Tokuda, and Ms.
Mizokami, Atsushi, Nakamoto, Masaru, Nakamura, Ritsuko, Namiki, Mikio, Ooi, Akishi, Oyama, Takeru, Tajiri, Ryosuke   +6 more
core   +1 more source

Primary malignant melanoma of the esophagus: A retrospective analysis of clinical features, management, and survival of 76 patients

Thoracic Cancer, 2019
Background Primary malignant melanoma of the esophagus (PMME) is rare. Patients with advanced melanoma of esophageal origin tend to have lower response rates to traditional therapies than those with other melanomas.
Xuan Wang, Yan Kong, Zhihong Chi, Xinan Sheng, Chuanliang Cui, Lili Mao, Bin Lian, Bixia Tang, Xieqiao Yan, Lu Si, Jun Guo   +10 more
doaj   +1 more source

A tissue-bioengineering strategy for modeling rare human kidney diseases in vivo

Nature Communications, 2021
The lack of animal models for some human diseases precludes our understanding of disease mechanisms and our ability to test new therapies in vivo. Here the authors present a tissue bioengineering strategy for the study of a rare kidney tumor called ...
J. O. R. Hernandez, X. Wang, M. Vazquez-Segoviano, M. Lopez-Marfil, M. F. Sobral-Reyes, A. Moran-Horowich, M. Sundberg, D. O. Lopez-Cantu, C. K. Probst, G. U. Ruiz-Esparza, K. Giannikou, R. Abdi, E. P. Henske, D. J. Kwiatkowski, M. Sahin, D. R. Lemos   +15 more
doaj   +1 more source

Weekly irinotecan in a patient with metastatic colorectal cancer on hemodialysis due to chronic renal failure [PDF]

, 2002
Background: The cytotoxic treatment of patients suffering from advanced or metastatic cancer undergoing hemodialysis due to chronic renal failure still remains a problem, since for those patients pharmacokinetic and pharmacodynamic data on most cytotoxic
Hacker, U., Heinemann, Volker, Schalhorn, A., Stemmler, J., Weise, A.   +4 more
core   +1 more source

Mannan-binding lectin serine protease-2 (MASP-2) in human kidney and its relevance for proteolytic activation of the epithelial sodium channel

Scientific Reports, 2022
Proteolytic activation of the renal epithelial sodium channel (ENaC) is increased by aldosterone. The aldosterone-sensitive protease remains unidentified.
Rikke Zachar, Steffen Thiel, Søren Hansen, Maiken Lumby Henriksen, Mikkel-Ole Skjoedt, Karsten Skjodt, Zohra Hamzaei, Kirsten Madsen, Lars Lund, Edith Hummler, Per Svenningsen, Boye Lagerbon Jensen   +11 more
doaj   +1 more source

Management of Melanoma Brain Metastases in the Era of Targeted Therapy

Journal of Skin Cancer, 2011
Disseminated metastatic disease, including brain metastases, is commonly encountered in malignant melanoma. The classical treatment approach for melanoma brain metastases has been neurosurgical resection followed by whole brain radiotherapy ...
Daniela Gonsalves Shapiro, Wolfram E. Samlowski   +1 more
doaj   +1 more source

Synchronous primary gastric and renal tumors: a case report

Future Science OA, 2023
Synchronous multiple primary cancers of the stomach and kidney are very rare, only 45 cases of synchronous multiple primary cancers of the stomach and kidney had been reported in the literature up until 2020.
Salma Merhaben, Asma Ben Mohamed, Amal Khsiba, Moufida Mahmoudi, Salwa Nechi, Emna Chelbi, Houda Kilani, Manel Yakoubi, Mohamed Lamine Hamzaoui, Mouna Medhioub, Mohamed Moussadak Azouz   +10 more
doaj   +1 more source

Tumors in von Hippel–Lindau Syndrome: From Head to Toe—Comprehensive State-of-the-Art Review [PDF]

, 2018
Von Hippel–Lindau syndrome (VHL) is an autosomal-dominant hereditary tumor disease that arises owing to germline mutations in the VHL gene, located on the short arm of chromosome 3.
Bhalla, Sanjeev, Ganeshan, Dhakshinamoorthy, Lubner, Meghan G., Menias, Christine O., Pickhardt, Perry J., Ramalingam, Preetha, Sandrasegaran, Kumaresan   +6 more
core   +1 more source

Pazopanib versus sunitinib in Chinese patients with locally advanced or metastatic renal cell carcinoma: pooled subgroup analysis from the randomized, COMPARZ studies

BMC Cancer, 2020
Background We performed a pooled analysis of the COMPARZ study assessing efficacy and safety of pazopanib versus sunitinib in treatment-naïve Chinese patients with locally advanced and/or metastatic renal cell carcinoma (a/mRCC).
Xinan Sheng, Jie Jin, Zhisong He, Yiran Huang, Aiping Zhou, Jinwan Wang, Xiubao Ren, Dingwei Ye, Xu Zhang, Shukui Qin, Fangjian Zhou, Binhui Wang, Jun Guo   +12 more
doaj   +1 more source