Results 141 to 150 of about 624,431 (182)

Hereditary renal hypouricemia in children

The Journal of Pediatrics, 1985
The renal handling of urate was investigated in four children with hereditary renal hypouricemia and in their parents. The urate/creatinine clearance ratios in the four patients were 1.02 +/- 0.28, 0.93 +/- 0.11, 1.03 +/- 0.24, and 1.46 +/- 0.26, markedly higher than those in control subjects.
E, Takeda, Y, Kuroda, M, Ito, K, Toshima, T, Watanabe, M, Ito, E, Naito, I, Yokota, T J, Hwang, M, Miyao   +9 more
openaire   +2 more sources

Insulin-Dependent Diabetes and Renal Hypouricemia

Nephron, 2008
We studied 14 patients (11 women and 3 men) from 18 to 33 years old, suffering from type I diabetes mellitus with normal renal function (creatinine clearance 106.91 ± 28.73 ml/min) and serum uric acid below 2.5 mg/dl (2.34 ± 0.11 mg/dl) as well as a high uric acid clearance (23.04 ± 5.92 ml/min) and fractional urate excretion (21.4 ± 2.6) versus urate ...
I, Magoula, G, Tsapas, K, Paletas, K, Mavromatidis   +3 more
openaire   +2 more sources

Severe Renal Hypouricemia Secondary to Hyperbilirubinemia

Nephron, 2008
A 64-year-old man with alcoholic liver cirrhosis had a progressive decrease in the serum uric acid (UA) until it became undetectable, an increase renal UA clearance, mild glycosuria with normal serum glucose and a decrease in the tubular reabsorption of phosphate in association with cholestasis secondary to a gallbladder carcinoma.
J A, Arranz-Caso, F J, Fernández de Paz, V, Barrio, L M, Cuadrado-Gomez, F, Albarran-Hernandez, M, Alvarez de Mon   +5 more
openaire   +2 more sources

Oxidative imbalance in idiopathic renal hypouricemia

Pediatric Nephrology, 2009
An important complication of idiopathic renal hypouricemia is exercise-induced acute renal failure (ARF). The most plausible explanation for this complication is that decreased antioxidant potential leads to kidney injury by reactive oxygen species (ROS).
Kazunari, Kaneko, Naho, Taniguchi, Yuko, Tanabe, Takahide, Nakano, Masafumi, Hasui, Kandai, Nozu   +5 more
openaire   +2 more sources

[Renal hypouricemia].

Nihon rinsho. Japanese journal of clinical medicine, 1997
Renal hypouricemia (serum urate < 2.0 mg/dl) is the inborn disorder due to the impaired tubular urate transport resulted in an increased urate excretion. The inheritance shows an autosomal recessive trait. The prevalence of renal hypouricemia is 0.15% in the outpatients.
I, Hisatome, M, Tsuboi, C, Shigemasa
openaire   +1 more source

Renal Hypouricemia with Both Drug-Insensitive Secretion and Defective Reabsorption of Urate: A Novel Type of Renal Hypouricemia

Nephron, 2008
Renal handling of urate in the hypouricemic patient with increase in both urate clearance (Cur) and Cur/creatinine clearance (Ccr) and normal urinary excretion of urate was studied according to the pharmacological evaluation. In the present case there was no response of urate excretion to either pyrazinamide or probenecid.
Ichiro Hisatome, Tatsuo Kato, Hiroyuki Miyakoda, Toru Takami, Takaaki Abe, Yasushi Tanaka, Hiromoto Kosaka, Kazuhide Ogino, Yasuo Mitani, Akio Yoshida, Hiroshi Kotake, Chiaki Shigemasa, Hiroto Mashiba, Ryoichi Sato, Akira Takeda   +14 more
openaire   +2 more sources

Renal Hypouricemia and Absorptive Hypercalciuria: A Real Syndrome

Nephron, 2008
We describe a case of renal hypouricemia due to increased tubular secretion of urate associated with absorptive hypercalciuria. This association has been described in the past, but this is the first time that high plasma levels of 1,25-dihydroxyvitamin D have been reported.
J, Uribarri, M S, Oh
openaire   +2 more sources

Exercise-induced acute renal failure in a patient with renal hypouricemia

Pediatric Nephrology, 2000
We describe a case of exercise-induced acute renal failure (ARF) in a patient with hypouricemia. Following recovery from ARF, the patient's serum urate concentration was 0.6-0.9 mg/dl, and the ratio of urate clearance to creatinine clearance (Cua/Ccr) was 41.9%-56.6%.
T, Watanabe, T, Abe, Y, Oda
openaire   +2 more sources

Acute renal failure after exercise in a child with renal hypouricemia

Pediatrics International, 1995
AbstractWe describe a 15 year old boy with renal hypouricemia who developed acute renal failure after a school athletics meeting, accompanied by appendicitis. During acute renal failure, the highest level of uric acid was 5.0 mg/dL, creatinine 7.9 mg/dL and urea nitrogen 58.6 mg/dL.
M, Fujieda, W, Yokoyama, N, Oishi, T, Okada, T, Kurashige, G, Hamada   +5 more
openaire   +2 more sources

Renal Hypouricemia due to an Isolated Renal Defect of Urate Transport

Nephron, 2008
A 22-year-old man was found to have low serum urate concentration (1.1–1.7 mg/dl). His urate clearance was markedly increased (26.9–35.5 ml/min) and was not decreased after administration of pyrazinamide, but was even more increased after administration of benzbromarone. No other renal tubular abnormalities were detected.
I, Hisatome, K, Ogino, M, Saito, J, Miyamoto, J, Hasegawa, H, Kotake, H, Mashiba, S, Nakamoto   +7 more
openaire   +2 more sources