Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Elephant trunk tip musculature reflects species differences in grasping behavior. [PDF]
Eigen L +6 more
europepmc +1 more source
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
Enhanced 3D Gaussian Splatting for Real-Scene Reconstruction via Depth Priors, Adaptive Densification, and Denoising. [PDF]
Shang H +7 more
europepmc +1 more source
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Improving the Quality and Value-Added Potential of Crude Pangasius Oil Extracted From Belly Byproducts via Rendering Methods. [PDF]
Lestari N +14 more
europepmc +1 more source
CaRo 2.0: sviluppo e valutazione di un software per il rendering interattivo ed espressivo di partiture musicali. [PDF]
Massimiliano Barichello
openalex
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Retraction: The Effect of Topical Benzydamine Hydrochloride and Cuff Pressure Monitorization on Postoperative Sore Throat Due to Intubation. [PDF]
Olgun Keleş B, Kaya M.
europepmc +1 more source
RENDERING VISIBLE: The underground organisational experience of the ANC-led Alliance until 1976
Raymond Suttner
openalex +1 more source

