Results 281 to 290 of about 22,544,156 (338)

Integrated multi‐omics analysis reveals metabolic reprogramming as a key driver of angiotensin II‐induced vascular remodeling

VIEW, EarlyView.
This study investigates the molecular alterations underlying angiotensin II (Ang II)‐induced vascular remodeling in cardiovascular diseases using a multi‐omics approach. Through data exploration and integrated multi‐omics analysis, our findings reveal that Ang II‐driven vascular injury in vascular smooth muscle cells is mediated by metabolic ...
Yiwei Hu, Dan Zhao, Lingyan Zhong, Jianxujie Zheng, Dongxue Zhang, Enhui Wu, Qian Shi, Liang Qiao, Ling Lin   +8 more
wiley   +1 more source

Chronic Copper Overload Triggers Inflammation in Mesenteric PVAT Alongside Changes in Renin-Angiotensin System-Related Pathways. [PDF]

Nutrients
Mawandji NBS, Lisboa NADS, Gomes KN, Vieira JM, Simão JJ, Alonso-Vale MI, Nunes KZ, Vassallo DV, Bolsoni-Lopes A.   +8 more
europepmc   +1 more source

Effect of ipsilateral ureteric obstruction on contralateral kidney and role of renin angiotensin system blockade on renal recovery in experimentally induced unilateral ureteric obstruction

, 2013
Minu Bajpai, ShasankaS Panda, Anand Sinha, Saumyaranjan Mallick, MeharC Sharma   +4 more
openalex   +1 more source

Inflammation as a Regulator of the Renin-Angiotensin System and Blood Pressure

Current Hypertension Reports, 2018
Ryousuke Satou, Harrison M Penrose, L. Navar   +2 more
semanticscholar   +1 more source

Hormone Replacement Therapy Uptake and Discontinuation Trends From 1996‐2023: An Observational Study of the Welsh Population

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To analyse prescribing trends for oral and transdermal hormone replacement therapy (HRT) in Wales from 1996 to 2023, including predictors of discontinuation within one year of initiation. Design Observational study using the Secure Anonymised Information Linkage (SAIL) databank.
Robin Andrews, Arron Lacey, Kate Bache, Emma J. Kidd   +3 more
wiley   +1 more source

Maintenance of blood pressure by reactive increases in plasma renin activity during salt depletion and renin-angiotensin system inhibition. [PDF]

J Hypertens
Sealey JE, Blumenfeld JD.
europepmc   +1 more source

The effect of chronic usage of Renin-Angiotensin-Aldosterone System Blocking Agents on Incidence of Contrast-Induced Nephropathy in patients with Diabetes Mellitus and Renal Insufficiency. A Restropesctive Cohort Study

, 2019
Astika Widy Utomo, Dwi Aris Agung Nugrahaningsih, Iwan Dwiprahasto   +2 more
openalex   +2 more sources

Bradycardia and Other Arrhythmias in Patients With Hepatorenal Syndrome‐Acute Kidney Injury Following Terlipressin Treatment: A Pooled Analysis of Three North American Phase III Clinical Studies

Alimentary Pharmacology &Therapeutics, EarlyView.
In a pooled analysis, bradycardia was observed in 6% of terlipressin‐treated patients but rarely required a dose interruption or reduction. Arrhythmia serious adverse event incidences were low and similar in both treatment groups. Routine intensive cardiac monitoring for the detection of arrhythmias may not be necessary during terlipressin ...
Jasmohan S. Bajaj, Paul Kwo, Stephen Chris Pappas, Jacqueline G. O'Leary, Khurram Jamil, Sanaz Cardoza, Florence Wong   +6 more
wiley   +1 more source

Efficacy of Esaxerenone Plus a Renin-Angiotensin System Inhibitor or Calcium Channel Blocker for Nocturnal Hypertension: A Post Hoc Analysis. [PDF]

Am J Hypertens
Kario K, Ito S, Itoh H, Rakugi H, Okuda Y, Yamakawa S.   +5 more
europepmc   +1 more source

Targeting acetylated high mobility group box 1 protein (HMGB1) and toll‐like receptor (TLR4) interaction to alleviate hypertension and neuroinflammation in fructose‐fed rats

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Our previous study reported that fructose intake increased systemic blood pressure and reduced nitric oxide (NO) in the nucleus tractus solitarius (NTS) due to oxidative stress and neuroinflammation. However, it remains unclear how reactive oxygen species (ROS) reduce NO and how this process impacts neuroinflammation in ...
Yu‐Te Lin, Chiu‐Yi Ho, Gwo‐Ching Sun, Tzyy‐Yue Wong, Michael Hsiao, Ching‐Jiunn Tseng, Pei‐Wen Cheng   +6 more
wiley   +1 more source