Results 321 to 330 of about 22,102,937 (361)

Autosomal Dominant Polycystic Kidney Disease Patients Requiring Nephrectomy: Characteristics and Surgical Considerations

ANZ Journal of Surgery, EarlyView.
ABSTRACT Background Nephrectomies are major surgeries often required in ADPKD for symptom control, removal of septic/malignant foci, and to create space for renal transplantation. Whether ADPKD patients should proceed with nephrectomy/ies should be guided by patient characteristics, technical considerations and anticipated risks and benefits. Methods A
Joel Ern Zher Chan, Kate S. Olakkengil, Shantanu Bhattacharjya, Santosh Antony Olakkengil   +3 more
wiley   +1 more source

Hypothesis: Reactive increases in plasma renin activity attenuate the fall in blood pressure caused by salt depletion and renin-angiotensin system inhibition. [PDF]

J Hypertens
Sealey JE, Blumenfeld JD.
europepmc   +1 more source

The flat glucose response curve during oral glucose tolerance tests in Chinese pregnant women and its association with adverse outcomes

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
A flat OGTT curve during pregnancy is associated with lower birth weight, and decreased risks of large for gestational age infants, macrosomia, gestational hypertension, and preeclampsia. Moreover, these risks varied based on maternal age and preconception BMI.
Ya Xi, Qianqian Wu, Binbin Yin, Jinghua Zhang, Yongying Bai   +4 more
wiley   +1 more source

Renin Is Essential for Angiotensin II Formation in the Brain

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
André F. Rodrigues, Oliver Domenig, Ingrid M. Garrelds, A.H. Jan Danser, Natalia Alenina, Marko Poglitsch, Michael Bader   +6 more
doaj   +1 more source

Kidney Renin-Angiotensin System: Lost in a RAS Cascade. [PDF]

Hypertension
Crowley SD, Navar LG, Prieto MC, Gurley SB, Coffman TM.   +4 more
europepmc   +1 more source

Targeting acetylated high mobility group box 1 protein (HMGB1) and toll‐like receptor (TLR4) interaction to alleviate hypertension and neuroinflammation in fructose‐fed rats

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Our previous study reported that fructose intake increased systemic blood pressure and reduced nitric oxide (NO) in the nucleus tractus solitarius (NTS) due to oxidative stress and neuroinflammation. However, it remains unclear how reactive oxygen species (ROS) reduce NO and how this process impacts neuroinflammation in ...
Yu‐Te Lin, Chiu‐Yi Ho, Gwo‐Ching Sun, Tzyy‐Yue Wong, Michael Hsiao, Ching‐Jiunn Tseng, Pei‐Wen Cheng   +6 more
wiley   +1 more source

Impact of renin-angiotensin system targeted therapy on aortic elastic properties assessed by computed tomography. [PDF]

Int J Cardiol Heart Vasc
Mileva N, Panayotov P, Hristova I, Koleva G, Georgieva D, Ivanova R, Vassilev D.   +6 more
europepmc   +1 more source

Stabilisation of PRCP by deubiquitinase‐targeting chimera (DUBTAC) to replenish autophagy for ameliorating pathological cardiac hypertrophy

British Journal of Pharmacology, EarlyView.
Background and Purpose Autophagy is essential for cellular homeostasis, and its impairment contributes to cardiac hypertrophy. Modulating autophagy has shown potential in treating pathological hypertrophy. Prolylcarboxypeptidase (PRCP), a lysosomal enzyme that hydrolyzes angiotensin II to Ang1‐7, has an unclear role in cardiac autophagy and hypertrophy.
Fangchao Zhou, Jun Xia, Yingjuan Liu, Wenqi He, Hongyuan Zhang, Bernard D. Keavney, Min Zi, Binh Y. Nguyen, Tamer M. A. Mohamed, Jessica M. Miller, Riham R. E. Abouleisa, Susanne S. Hille, Elizabeth J. Cartwright, Oliver J. Müller, Honglin Xu, Sam Butterworth, Xin Wang   +16 more
wiley   +1 more source

Fasting recovers age-related hypertension in the rats: reset of renal renin-angiotensin system components and klotho. [PDF]

BMC Nephrol
Badreh F, Joukar S, Badavi M, Rashno M.
europepmc   +1 more source

The thoracic perivascular adipose tissue spontaneously induces vasoconstriction through activation of α1‐adrenoceptors

British Journal of Pharmacology, EarlyView.
Background and Purpose Although perivascular adipose tissue (PVAT) contains substances with contractile properties, its actions on the vascular tone are associated with the release of anticontractile substances. We hypothesize that procontractile PVAT products also exert direct effects on vascular tone. Experimental Approach Thoracic aortas from Wistar
Leonardo Gomes‐Pereira, José Eduardo da Silva‐Santos   +1 more
wiley   +1 more source