Results 91 to 100 of about 251,836 (347)

Different behaviour of the N-terminal and C-terminal fragment of proatrial natriuretic factor in plasma of healthy subjects as well as of patients with cirrhosis [PDF]

, 1990
N-terminal (atrial natriuretic factor (ANF) 1-98) and C-terminal (ANF 99-126) fragments of proatrial natriuretic factor (NTA and CTA, respectively) were determined in plasma of healthy subjects adopting different postures and in patients with cirrhosis ...
Arendt, Rainer M., Cantin, M., Gerbes, Alexander L., Paumgartner, Gustav, Thibault, G., Vollmar, Angelika M.   +5 more
core   +1 more source

Inhibition of renin and the (pro)renin receptor system

Blood Pressure, 2012
Renin is the rate-limiting step of the renin-angiotensin system (RAS) and can induce hypertension and cardiovascular diseases (CVDs) through the over-activated renin-angiotensin-converting enzyme (ACE)-angiotensin (Ang) II-Ang II type 1 receptor (AT(1)R) axis.
Robert D. Phillips, Franco Milani, Cuie Guang, Bo Jiang   +3 more
openaire   +3 more sources

Estimation of Plasma Volume by Machine Learning to Improve the Interpretation of the Athlete Biological Passport

Drug Testing and Analysis, EarlyView.
A new machine learning model for plasma volume (PV) estimation was applied within the ABP framework. PV estimation was applied through visual displays or corrected ABP thresholds. With a favorable assessment from ABP experts, these results support further application of this model in the presence of specific confounding factors.
Bastien Krumm, Laura Lewis, Jakob Mørkeberg, Yorck Olaf Schumacher, Giuseppe d'Onofrio, Basile Moreillon, Raphael Faiss   +6 more
wiley   +1 more source

Systemic aging fuels heart failure: Molecular mechanisms and therapeutic avenues

ESC Heart Failure, Volume 12, Issue 2, Page 1059-1080, April 2025.
Abstract Systemic aging influences various physiological processes and contributes to structural and functional decline in cardiac tissue. These alterations include an increased incidence of left ventricular hypertrophy, a decline in left ventricular diastolic function, left atrial dilation, atrial fibrillation, myocardial fibrosis and cardiac ...
Zhuyubing Fang, Umar Raza, Jia Song, Junyan Lu, Shun Yao, Xiaohong Liu, Wei Zhang, Shujuan Li   +7 more
wiley   +1 more source

Serum Renin and Renin Substrate Levels in Scleroderma

Experimental Biology and Medicine, 1975
Scleroderma is a disease of mesenchymal tissues characterized by fibrosis and vascular changes which eventually lead to organ insufficiency. Two clinical forms have been recognized, localized and systemic scleroderma. The localized form only affects the skin and the lesions have a tendency to resolve spontaneously. Systemic scleroderma is a progressive,
Anne B. Gould, Raul Fleischmajer
openaire   +3 more sources

Meta‐analysis of sotagliflozin, a dual sodium‐glucose‐cotransporter 1/2 inhibitor, for heart failure in type 2 diabetes

ESC Heart Failure, Volume 12, Issue 2, Page 968-979, April 2025.
Abstract Sodium‐glucose co‐transporters (SGLTs) mediate sodium and glucose transport across cell membranes. SGLT2 inhibitors have a recognized place within heart failure (HF) guidelines. We evaluated the effect of sotagliflozin on HF and cardiovascular outcomes in participants with type 2 diabetes. Scopus, Medline, Embase and Central were searched from
Maria Anna Bantounou, Panagiotis Sardellis, Josip Plascevic, Ribeya Awaes‐Mahmood, Justyna Kaczmarek, Daniel Black Boada, Rosa Thuemmler, Sam Philip   +7 more
wiley   +1 more source

Protective Effects of Nanoparticle-Loaded Aliskiren on Cardiovascular System in Spontaneously Hypertensive Rats

Molecules, 2019
Aliskiren, a renin inhibitor, has been shown to have cardioprotective and blood pressure (BP) lowering effects. We aimed to determine the effects of nanoparticle-loaded aliskiren on BP, nitric oxide synthase activity (NOS) and structural alterations of ...
Olga Pechanova, Andrej Barta, Martina Koneracka, Vlasta Zavisova, Martina Kubovcikova, Jana Klimentova, Jozef Tӧrӧk, Anna Zemancikova, Martina Cebova   +8 more
doaj   +1 more source

N‐terminal pro‐brain natriuretic peptide and cardiorenal outcome in patients with anaemia in chronic kidney disease

ESC Heart Failure, Volume 12, Issue 2, Page 848-858, April 2025.
Abstract Aims Blood levels of N‐terminal pro‐brain natriuretic peptide (NT‐proBNP) may be modified by low renal clearance and anaemia. The aim of this study was to investigate the impact of the blood NT‐proBNP level on cardiovascular and renal outcomes in patients with these two manifestations.
Hiroshi Nishi, Masaomi Nangaku, Tadashi Sofue, Tatsuo Kagimura, Ichiei Narita   +4 more
wiley   +1 more source

Mechanisms of hypertension during and after orthotopic liver transplantation in children [PDF]

, 1989
The aim of this study was to assess the hormonal alterations that may mediate the systemic hypertension that develops in patients during the perioperative period of orthotopic liver transplantation.
Akerstedt, Andrews, Ann Thompson, Arroyo, Bantle, Bantle, Baxter, Baylis, Bellet, Bernardi, Better, Bland, Bomzon, Bonjour, Borland, Busuttil, Cappuccio, Carlos Esquivel, Chrymko, Clement de Clety, Curtis, D. Ryan Cook, Demetrius Ellis, Epstein, Eskay, Filep, Floras, Gaillard, Gardner, Gartner, Gentile, Gerr, Glantz, Graystone, Henriksen, Hiatt, Januszewicz, Kimura, Kohno, Lau, Ledsome, Leslie, Loughran, Lustig, Mason, Minuk, Moss, Murrey, Nakai, Nicholls, Oaks, Ogawa, Palestine, Papadakis, Powell-Jackson, Ring-Larsen, Ring-Larsen, Rosanto, Salazar, Schacter, Seino, Shapiro, Skorecki, Starzl, Stephen Lawless, Task Force on Blood Pressure Control in Children, Thomas Starzl, Thompson, Vacanti, Voorhees, Weidle, Weidmann, Williams   +72 more
core   +1 more source

RENIN ANGIOTENSIN SYSTEM IN THE CONTEXT OF RENIN, PRORENIN, AND THE (PRO)RENIN RECEPTOR

Reviews in Agricultural Science, 2013
Since the discovery of renin by Tigerstedt in 1898, the complex roles of the components of the renin angiotensin system (RAS)have been extensively studied. RAS is involved in maintaining the homeostasis of body fluids and thus regulates the blood pressure.Renin is the key regulatory enzyme of RAS that catalyzes its only substrate angiotensinogen into ...
Tsutomu Nakagawa, Fumiaki Suzuki, Akio Ebihara, Ahm Nurun Nabi, Kazal Boron Biswas   +4 more
openaire   +2 more sources